Findings

What do systematic reviews say?

3 questions · 5 findings · 1 reviews

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No studies found 0 · 0%GRADE not reported 0 · 0%Very low 2 · 40%Low 0 · 0%Moderate 3 · 60%High 0 · 0%

Tacrolimus 0.1% vs corticosteroids

Adverse effects ‐ burning · people with atopic dermatitis

Tacrolimus 0.1% probably leads to higher adverse effects: burning ‐ tacrolimus 0.1% versus hydrocortisone… compared with corticosteroids (moderate certainty).

3 findings from 1 review

Topical tacrolimus for atopic dermatitis 2015 · Cochrane Headline outcomes only
RR 2.91 [1.6, 5.28]
1 study · 371 participants
Moderate
Topical tacrolimus for atopic dermatitis 2015 · Cochrane Headline outcomes only
RR 4.59 [3.1, 6.78]
1 study · 377 participants
Moderate
Topical tacrolimus for atopic dermatitis 2015 · Cochrane Headline outcomes only
RR 3.79 [2.99, 4.81]
1 study · 972 participants
Moderate

Tacrolimus 0.1% vs ciclosporin

Adverse effects · people with atopic dermatitis

It is very uncertain whether tacrolimus 0.1% changes adverse effects compared with ciclosporin (very low certainty).

1 finding from 1 review

Topical tacrolimus for atopic dermatitis 2015 · Cochrane Headline outcomes only
RR 1 [0.31, 3.28]
1 study · 30 participants
Very low

Tacrolimus 0.1% vs pimecrolimus 1%

Adverse effects ‐ 6 weeks · people with atopic dermatitis

It is very uncertain whether tacrolimus 0.1% changes adverse effects ‐ 6 weeks compared with pimecrolimus 1% (very low certainty).

1 finding from 1 review

Topical tacrolimus for atopic dermatitis 2015 · Cochrane Headline outcomes only
RR 0.89 [0.47, 1.71]
2 studies · 506 participants
Very low