Findings

What do systematic reviews say?

3 questions · 3 findings · 1 reviews

No studies found 0 · 0%GRADE not reported 0 · 0%Very low 1 · 33.3%Low 2 · 66.7%Moderate 0 · 0%High 0 · 0%

Clinical improvement · adults with refractory, moderate‐to‐severe ulcerative colitis

Tacrolimus showed no clear difference in clinical improvement compared with beclometasone (low certainty).

1 finding from 1 review

Clinical improvement · adults with refractory, moderate‐to‐severe ulcerative colitis

Tacrolimus may leads to higher clinical improvement compared with placebo (low certainty).

1 finding from 1 review

Clinical improvement · adults with refractory, moderate‐to‐severe ulcerative colitis

It is very uncertain whether tacrolimus changes clinical improvement compared with ciclosporin (very low certainty).

1 finding from 1 review

Tacrolimus (FK506) for induction of remission in corticosteroid‐refractory ulcerative colitis 2022 · Cochrane Headline outcomes only
RR 0.9 [0.7, 1.16]
1 study · 113 participants
Very low