What do systematic reviews say?

Systemic antibiotics alone vs systematic antibiotics plus antibiotic lock solution

The review found no eligible studies for this question.

• Interventions for treating catheter‐related bloodstream infections in people receiving maintenance haemodialysis 2022 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Systemic antibiotics plus antibiotic lock solutions plus tissue plasminogen activator vs systemic antibiotics plus antibiotic lock solutions plus heparin

The review found no eligible studies for this question.

• Interventions for treating catheter‐related bloodstream infections in people receiving maintenance haemodialysis 2022 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Single preoperative dose of systemic antibiotics (clindamycin 600 mg), total chemo-mechanical debridement and root filling vs Matched placebo, total chemo-mechanical debridement and root filling

• Systemic antibiotics for symptomatic apical periodontitis and acute apical abscess in adults 2024 · Cochrane All outcomes

  7 days
  No adverse effects reported in the placebo group; 1 participant reported dizziness in the intervention group. 72 participants (1 study).
  1 study · 72 participants
  Low

Postoperative systemic antibiotics (phenoxymethylpenicillin/penicillin VK, 7-day course), partial or total chemo-mechanical debridement and analgesics vs Matched placebo, partial or total chemo-mechanical debridement and analgesics

• Systemic antibiotics for symptomatic apical periodontitis and acute apical abscess in adults 2024 · Cochrane All outcomes

  3 days
  1 participant reported diarrhoea (placebo group); 1 participant reported fatigue and reduced energy postoperatively (antibiotic group). 61 participants (2 studies).
  2 studies · 61 participants
  Very low