Findings

What do systematic reviews say?

4 questions · 4 findings · 1 reviews · Headline outcomes only

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No studies found 1 · 25%GRADE not reported 0 · 0%Very low 0 · 0%Low 3 · 75%Moderate 0 · 0%High 0 · 0%

Systemic aminocaproic acid vs placebo

Short‐term visual acuity 20/40 or better ≤ 2 weeks after treatment · people with traumatic hyphema

Systemic aminocaproic acid showed no clear difference in short‐term visual acuity 20/40 or better ≤ 2 weeks after treatment compared with placebo (low certainty).

1 finding from 1 review

Medical interventions for traumatic hyphema 2023 · Cochrane Headline outcomes only
RR 0.87 [0.57, 1.32]
1 study · 34 participants
Low

Systemic aminocaproic acid vs placebo

Medium‐term visual acuity 20/40 or better > 2 weeks and ≤ 2 months after treatment · people with traumatic hyphema

The review found no eligible studies for this question.

1 finding from 1 review

Medical interventions for traumatic hyphema 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Systemic aminocaproic acid vs placebo

Long‐term visual acuity 20/40 or better > 2 months after treatment · people with traumatic hyphema

Systemic aminocaproic acid showed no clear difference in long‐term visual acuity 20/40 or better > 2 months after treatment compared with placebo (low certainty).

1 finding from 1 review

Medical interventions for traumatic hyphema 2023 · Cochrane Headline outcomes only
RR 1.03 [0.82, 1.29]
2 studies · 108 participants
Low

Systemic aminocaproic acid vs placebo

Final visual acuity 20/40 or better at resolution of hyphema · people with traumatic hyphema

Systemic aminocaproic acid showed no clear difference in final visual acuity 20/40 or better at resolution of hyphema compared with placebo (low certainty).

1 finding from 1 review

Medical interventions for traumatic hyphema 2023 · Cochrane Headline outcomes only
RR 1.05 [0.93, 1.18]
2 studies · 143 participants
Low