Findings

What do systematic reviews say?

7 questions · 7 findings · 1 reviews · Eyes and Vision

Sort:Best matchNewest Highest certainty Download CSV

No studies found 1 · 14.3%GRADE not reported 0 · 0%Very low 0 · 0%Low 5 · 71.4%Moderate 1 · 14.3%High 0 · 0%

Systemic aminocaproic acid vs placebo

Short‐term visual acuity 20/40 or better ≤ 2 weeks after treatment · people with traumatic hyphema

Systemic aminocaproic acid showed no clear difference in short‐term visual acuity 20/40 or better ≤ 2 weeks after treatment compared with placebo (low certainty).

1 finding from 1 review

Medical interventions for traumatic hyphema 2023 · Cochrane Headline outcomes only
RR 0.87 [0.57, 1.32]
1 study · 34 participants
Low

Systemic aminocaproic acid vs placebo

Medium‐term visual acuity 20/40 or better > 2 weeks and ≤ 2 months after treatment · people with traumatic hyphema

The review found no eligible studies for this question.

1 finding from 1 review

Medical interventions for traumatic hyphema 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Systemic aminocaproic acid vs placebo

Long‐term visual acuity 20/40 or better > 2 months after treatment · people with traumatic hyphema

Systemic aminocaproic acid showed no clear difference in long‐term visual acuity 20/40 or better > 2 months after treatment compared with placebo (low certainty).

1 finding from 1 review

Medical interventions for traumatic hyphema 2023 · Cochrane Headline outcomes only
RR 1.03 [0.82, 1.29]
2 studies · 108 participants
Low

Systemic aminocaproic acid vs placebo

Final visual acuity 20/40 or better at resolution of hyphema · people with traumatic hyphema

Systemic aminocaproic acid showed no clear difference in final visual acuity 20/40 or better at resolution of hyphema compared with placebo (low certainty).

1 finding from 1 review

Medical interventions for traumatic hyphema 2023 · Cochrane Headline outcomes only
RR 1.05 [0.93, 1.18]
2 studies · 143 participants
Low

Systemic aminocaproic acid vs placebo

Time to resolution of primary hemorrhage · people with traumatic hyphema

1 finding from 1 review

Medical interventions for traumatic hyphema 2023 · Cochrane Headline outcomes only
no estimate extracted
6 studies · 330 participants
Low

Systemic aminocaproic acid vs placebo

Secondary hemorrhage at any time point · people with traumatic hyphema

Systemic aminocaproic acid may leads to lower secondary hemorrhage at any time point compared with placebo (low certainty).

1 finding from 1 review

Medical interventions for traumatic hyphema 2023 · Cochrane Headline outcomes only
RR 0.28 [0.13, 0.6]
6 studies · 330 participants
Low

Systemic aminocaproic acid vs placebo

Adverse event nausea and vomiting (0 to 24 hours) · people with traumatic hyphema

Systemic aminocaproic acid probably leads to higher adverse effects: nausea or vomiting compared with placebo (moderate certainty).

1 finding from 1 review

Medical interventions for traumatic hyphema 2023 · Cochrane Headline outcomes only
RR 8.6 [2.09, 35.5]
3 studies · 131 participants
Moderate