Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

144 questions · 146 findings · 24 reviews

No studies found 67 · 45.9%GRADE not reported 7 · 4.8%Very low 35 · 24%Low 26 · 17.8%Moderate 8 · 5.5%High 3 · 2.1%

Surgical interventions (exploration and decompression / external neurolysis, internal neurolysis, neurorrhaphy / direct repair, neuroma excision, anastomosis, autologous or allograft nerve grafting or tubulization) vs non‐surgical treatment

Quality of life · Adults with symptomatic mild to moderate knee osteoarthritis defined as knee pain and radiographic evidence of non‐end stage…

The review found no eligible studies for this question.

1 finding from 1 review

Open (surgical) reduction and fixation vs Closed (non-surgical) treatment

Outcome not reported · Adults (16 to 68 years) with mandibular fractures excluding condylar involvement

The review found no eligible studies for this question.

1 finding from 1 review
  • "There were no studies comparing different types of closed interventions with one another or comparing open and closed interventions." "We found no studies that compared surgical with non-surgical treatments."
    0 studies
    No studies found

Surgical reimplantation of ureters plus antibiotics vs antibiotics alone

New renal parenchymal defects (scars and thinning) on IVP: unit of analysis (children) at 4 to 5 years: surgical correction + antibiotics versus antibiotics alone · primary VUR

Surgical reimplantation of ureters plus antibiotics showed no clear difference in new renal parenchymal defects (scars and thinning) on IVP: unit of… compared with antibiotics alone (moderate certainty).

1 finding from 1 review

Surgical reimplantation of ureters plus antibiotics vs antibiotics alone

Correction of VUR: unit of analysis (children) after 3 years: surgical correction + antibiotics versus antibiotics alone · primary VUR

It is very uncertain whether surgical reimplantation of ureters plus antibiotics changes correction of VUR: unit of analysis (children) after 3 years:… compared with antibiotics alone (very low certainty).

1 finding from 1 review

Surgical reimplantation of ureters plus antibiotics vs antibiotics alone

Febrile UTI by 5 years: surgical correction + antibiotics versus antibiotics alone · primary VUR

Surgical reimplantation of ureters plus antibiotics probably leads to lower febrile UTI by 5 years: surgical correction + antibiotics versus… compared with antibiotics alone (moderate certainty).

1 finding from 1 review

Any experimental intervention (surgical or non-surgical) vs None (placebo or no treatment)

Improvement in nutritional intake · People of any age and either sex, in any setting, with BRONJ; bisphosphonate exposure past or current; includes people with cancer and…

The review found no eligible studies for this question.

1 finding from 1 review

Any experimental intervention (surgical or non-surgical) vs active control

Healing of osteonecrosis - improvement ('healed' or 'improved' vs 'unchanged' or 'worse') · People of any age and either sex, in any setting, with BRONJ; bisphosphonate exposure past or current; includes people with cancer and…

The review found no eligible studies for this question.

1 finding from 1 review

Any experimental intervention (surgical or non-surgical) vs None (placebo or no treatment)

Improvement of pre-existing accompanying symptoms other than pain · People of any age and either sex, in any setting, with BRONJ; bisphosphonate exposure past or current; includes people with cancer and…

The review found no eligible studies for this question.

1 finding from 1 review

Any experimental intervention (surgical or non-surgical) vs None (placebo or no treatment)

Mortality rate and cause of death · People of any age and either sex, in any setting, with BRONJ; bisphosphonate exposure past or current; includes people with cancer and…

The review found no eligible studies for this question.

1 finding from 1 review