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Evidence found and GRADE certainty

9 questions · 9 findings · 1 reviews · Neonatal

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No studies found 2 · 22.2%GRADE not reported 0 · 0%Very low 1 · 11.1%Low 6 · 66.7%Moderate 0 · 0%High 0 · 0%

Surfactant administration via laryngeal mask airway (S‐LMA) vs surfactant administration via endotracheal tube (ETT) with the intent to rapidly extubate (InSurE)

Death or bronchopulmonary dysplasia · preterm infants with or at risk of respiratory distress syndrome

Surfactant administration via laryngeal mask airway (S‐LMA) showed no clear difference in death or bronchopulmonary dysplasia compared with surfactant administration via endotracheal tube (ETT) with the… (low certainty).

1 finding from 1 review

Surfactant administration via laryngeal mask airway (S‐LMA) vs surfactant administration through an endotracheal tube (S‐ETT)

Pulmonary air leak · preterm infants with or at risk of respiratory distress syndrome

It is very uncertain whether surfactant administration via laryngeal mask airway (S‐LMA) changes pulmonary air leak, any (during first hospitalisation) Anytime to… compared with surfactant administration via endotracheal tube (ETT) with… (very low certainty).

1 finding from 1 review

Surfactant administration via laryngeal mask airway (S‐LMA) vs surfactant administration through an endotracheal tube (S‐ETT)

Bronchopulmonary dysplasia · preterm infants with or at risk of respiratory distress syndrome

The review found no eligible studies for this question.

1 finding from 1 review

Surfactant administration via laryngeal mask airway (S‐LMA) vs no surfactant administration

Death or bronchopulmonary dysplasia · preterm infants with or at risk of respiratory distress syndrome

Surfactant administration via laryngeal mask airway (S‐LMA) showed no clear difference in death or bronchopulmonary dysplasia compared with no surfactant administration (low certainty).

1 finding from 1 review

Surfactant administration via laryngeal mask airway (S‐LMA) vs no surfactant administration

Pulmonary air leak · preterm infants with or at risk of respiratory distress syndrome

Surfactant administration via laryngeal mask airway (S‐LMA) showed no clear difference in pulmonary air leak, any (during first hospitalisation) Anytime to… compared with no surfactant administration (low certainty).

1 finding from 1 review

Surfactant administration via laryngeal mask airway (S‐LMA) vs no surfactant administration

Bronchopulmonary dysplasia · preterm infants with or at risk of respiratory distress syndrome

Surfactant administration via laryngeal mask airway (S‐LMA) showed no clear difference in bronchopulmonary dysplasia (clinical definition) among survivors compared with no surfactant administration (low certainty).

1 finding from 1 review

Surfactant administration via laryngeal mask airway (S‐LMA) vs surfactant administration via endotracheal tube (ETT) with the intent to rapidly extubate (InSurE)

Pulmonary air leak · preterm infants with or at risk of respiratory distress syndrome

Surfactant administration via laryngeal mask airway (S‐LMA) showed no clear difference in pulmonary air leak, any (during first hospitalisation) Anytime to… compared with surfactant administration via endotracheal tube (ETT) with the… (low certainty).

1 finding from 1 review

Surfactant administration via laryngeal mask airway (S‐LMA) vs surfactant administration via endotracheal tube (ETT) with the intent to rapidly extubate (InSurE)

Bronchopulmonary dysplasia · preterm infants with or at risk of respiratory distress syndrome

Surfactant administration via laryngeal mask airway (S‐LMA) showed no clear difference in bronchopulmonary dysplasia (clinical definition) among survivors compared with surfactant administration via endotracheal tube (ETT) with the… (low certainty).

1 finding from 1 review

Surfactant administration via laryngeal mask airway (S‐LMA) vs surfactant administration through an endotracheal tube (S‐ETT)

Death or bronchopulmonary dysplasia · preterm infants with or at risk of respiratory distress syndrome

The review found no eligible studies for this question.

1 finding from 1 review