Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

9 questions · 9 findings · 1 reviews

No studies found 4 · 44.4%GRADE not reported 0 · 0%Very low 4 · 44.4%Low 1 · 11.1%Moderate 0 · 0%High 0 · 0%

Phenobarbital vs phenytoin

Proportion of infants who achieve seizure control after maximal loading dose of ASM · neonates with EEG‐confirmed seizures

It is very uncertain whether summary of findings table ‐ Phenobarbital changes proportion of infants who achieve seizure control after the maximal… compared with phenytoin (very low certainty).

1 finding from 1 review

Phenobarbital vs phenytoin

Proportion of infants who achieve seizure control after the first loading dose of ASM · neonates with clinically diagnosed seizures

Summary of findings table ‐ Phenobarbital may leads to higher proportion of infants who achieve seizure control after first… compared with phenytoin (low certainty).

1 finding from 1 review

Phenobarbital vs phenytoin

Mortality before hospital discharge · neonates with clinically diagnosed seizures

It is very uncertain whether summary of findings table ‐ Phenobarbital changes mortality before hospital discharge compared with phenytoin (very low certainty).

1 finding from 1 review

Phenobarbital vs phenytoin

Need for mechanical ventilation · neonates with clinically diagnosed seizures

It is very uncertain whether summary of findings table ‐ Phenobarbital changes requirement of mechanical ventilation compared with phenytoin (very low certainty).

1 finding from 1 review

Phenobarbital vs phenytoin

Proportion of infants who develop sedation or drowsiness · neonates with clinically diagnosed seizures

It is very uncertain whether summary of findings table ‐ Phenobarbital changes proportion of infants who develop sedation or drowsiness compared with phenytoin (very low certainty).

1 finding from 1 review