Proportion of infants who achieve seizure control after the first loading dose of ASM · neonates with EEG‐confirmed seizures
Summary of findings table ‐ Phenobarbital + bumetanide showed no clear difference in proportion of infants who achieve seizure control after the first… compared with phenobarbital alone (low certainty).
1 finding from 1 review
Proportion of infants who achieve seizure control after maximal loading dose of ASM · neonates with EEG‐confirmed seizures
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Mortality or neurodevelopmental disability at 18 to 24 months' corrected age ‐ not reported · neonates with EEG‐confirmed seizures
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Mortality before hospital discharge · neonates with EEG‐confirmed seizures
It is very uncertain whether summary of findings table ‐ Phenobarbital + bumetanide changes mortality before hospital discharge compared with phenobarbital alone (very low certainty).
1 finding from 1 review
Cognitive impairment · neonates with EEG‐confirmed seizures
It is very uncertain whether summary of findings table ‐ Phenobarbital + bumetanide changes cognitive impairment at 18‐24 months compared with phenobarbital alone (very low certainty).
1 finding from 1 review
Need for mechanical ventilation · neonates with EEG‐confirmed seizures
1 finding from 1 review
no estimate extracted
1 study · 1 participants
GRADE not reported
Proportion of infants who develop epilepsy post‐discharge · neonates with EEG‐confirmed seizures
It is very uncertain whether summary of findings table ‐ Phenobarbital + bumetanide changes proportion of infants who develop epilepsy post‐discharge compared with phenobarbital alone (very low certainty).
1 finding from 1 review
Proportion of infants who achieve seizure control after the first loading dose of ASM · neonates with EEG‐confirmed seizures
Summary of findings table ‐ Phenobarbital probably leads to higher proportion of infants who achieve seizure control after the first… compared with levetiracetam (moderate certainty).
1 finding from 1 review
Mortality or neurodevelopmental disability at 18 to 24 months' corrected age ‐ not reported · neonates with clinically diagnosed seizures
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Mortality before hospital discharge · neonates with clinically diagnosed seizures
Summary of findings table ‐ Phenobarbital showed no clear difference in mortality before hospital discharge compared with levetiracetam (low certainty).
1 finding from 1 review
Need for mechanical ventilation · neonates with clinically diagnosed seizures
It is very uncertain whether summary of findings table ‐ Phenobarbital changes requirement of mechanical ventilation compared with levetiracetam (very low certainty).
1 finding from 1 review
Proportion of infants who develop sedation or drowsiness · neonates with clinically diagnosed seizures
It is very uncertain whether summary of findings table ‐ Phenobarbital changes proportion of infants who develop sedation or drowsiness compared with levetiracetam (very low certainty).
1 finding from 1 review
Proportion of infants who develop epilepsy post‐discharge · neonates with clinically diagnosed seizures
It is very uncertain whether summary of findings table ‐ Phenobarbital changes proportion of infants who develop epilepsy post discharge compared with levetiracetam (very low certainty).
1 finding from 1 review
Proportion of infants who achieve seizure control after the first loading dose of ASM · neonates with EEG‐confirmed seizures
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Proportion of infants who achieve seizure control after maximal loading dose of ASM · neonates with EEG‐confirmed seizures
It is very uncertain whether summary of findings table ‐ Phenobarbital changes proportion of infants who achieve seizure control after the maximal… compared with phenytoin (very low certainty).
1 finding from 1 review
Mortality or neurodevelopmental disability at 18 to 24 months' corrected age ‐ not reported · neonates with EEG‐confirmed seizures
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Proportion of infants who achieve seizure control after the first loading dose of ASM · neonates with clinically diagnosed seizures
Summary of findings table ‐ Phenobarbital may leads to higher proportion of infants who achieve seizure control after first… compared with phenytoin (low certainty).
1 finding from 1 review
Proportion of infants who achieve seizure control after maximal loading dose of ASM · neonates with clinically diagnosed seizures
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Proportion of infants who achieve seizure control after maximal loading dose of ASM · neonates with EEG‐confirmed seizures
Summary of findings table ‐ Phenobarbital probably leads to higher proportion of infants who achieve seizure control after the maximal… compared with levetiracetam (moderate certainty).
1 finding from 1 review
Mortality or neurodevelopmental disability at 18 to 24 months' corrected age ‐ not reported · neonates with clinically diagnosed seizures
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found