What do systematic reviews say?

Phenobarbital vs phenytoin

It is very uncertain whether summary of findings table ‐ Phenobarbital changes proportion of infants who achieve seizure control after the maximal… compared with phenytoin (very low certainty).

• Anti‐seizure medications for neonates with seizures 2023 · Cochrane Headline outcomes only
  RR 0.97 [0.54, 1.72]
  1 study · 59 participants
  Very low