Findings

What do systematic reviews say?

2 questions · 2 findings · 1 reviews

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No studies found 0 · 0%GRADE not reported 0 · 0%Very low 1 · 50%Low 1 · 50%Moderate 0 · 0%High 0 · 0%

Phenobarbital vs levetiracetam

Mortality before hospital discharge · neonates with clinically diagnosed seizures

Summary of findings table ‐ Phenobarbital showed no clear difference in mortality before hospital discharge compared with levetiracetam (low certainty).

1 finding from 1 review

Anti‐seizure medications for neonates with seizures 2023 · Cochrane Headline outcomes only
RR 1.41 [0.82, 2.43]
6 studies · 452 participants
Low

Phenobarbital vs levetiracetam

Mortality before hospital discharge · neonates with EEG‐confirmed seizures

It is very uncertain whether summary of findings table ‐ Phenobarbital changes mortality before hospital discharge compared with levetiracetam (very low certainty).

1 finding from 1 review

Anti‐seizure medications for neonates with seizures 2023 · Cochrane Headline outcomes only
RR 0.3 [0.04, 2.52]
1 study · 106 participants
Very low