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Evidence found and GRADE certainty

7 questions · 7 findings · 1 reviews · Gynaecology and Fertility

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No studies found 2 · 28.6%GRADE not reported 0 · 0%Very low 4 · 57.1%Low 1 · 14.3%Moderate 0 · 0%High 0 · 0%

Summary of findings table ‐ Metformin + megestrol vs megestrol

Progression of endometrial hyperplasia to endometrial cancer · endometrial hyerplasia

It is very uncertain whether summary of findings table ‐ Metformin + megestrol changes progression of endometrial hyperplasia to endometrial cancer compared with megestrol (very low certainty).

1 finding from 1 review

Summary of findings table ‐ Metformin + megestrol vs megestrol

Regression of endometrial hyperplasia (with or without atypia) to proliferative, secretory, or atrophic endometrium · endometrial hyerplasia

Summary of findings table ‐ Metformin + megestrol may leads to higher regression of endometrial hyperplasia (with or without atypia) to… compared with megestrol (low certainty).

1 finding from 1 review