Findings

What do systematic reviews say?

7 questions · 7 findings · 1 reviews · Gynaecological, Neuro-oncology and Orphan Cancer

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No studies found 0 · 0%GRADE not reported 0 · 0%Very low 3 · 42.9%Low 4 · 57.1%Moderate 0 · 0%High 0 · 0%

Lifestyle interventions vs placebo or usual care

Overall survival (12 months) · weight reduction in obesity to improve survival in women with endometrial cancer

1 finding from 1 review

Interventions for weight reduction in obesity to improve survival in women with endometrial cancer 2023 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 2 participants
Low

Lifestyle interventions vs placebo or usual care

Overall survival (24 months) · weight reduction in obesity to improve survival in women with endometrial cancer

It is very uncertain whether summary of findings table ‐ Lifestyle intervention changes overall survival (24 months) compared with usual care compared to placebo (very low certainty).

1 finding from 1 review

Interventions for weight reduction in obesity to improve survival in women with endometrial cancer 2023 · Cochrane Headline outcomes only
RR 0.23 [0.01, 4.55]
1 study · 37 participants
Very low

Lifestyle interventions vs placebo or usual care

Adverse events – musculoskeletal · weight reduction in obesity to improve survival in women with endometrial cancer

It is very uncertain whether summary of findings table ‐ Lifestyle intervention changes adverse events – musculoskeletal compared with usual care compared to placebo (very low certainty).

1 finding from 1 review

Interventions for weight reduction in obesity to improve survival in women with endometrial cancer 2023 · Cochrane Headline outcomes only
RR 19.03 [1.17, 310.52]
8 studies · 315 participants
Very low

Lifestyle interventions vs placebo or usual care

Cancer‐specific survival (24 months) (Number of cancer‐related deaths) · weight reduction in obesity to improve survival in women with endometrial cancer

1 finding from 1 review

Interventions for weight reduction in obesity to improve survival in women with endometrial cancer 2023 · Cochrane Headline outcomes only
no estimate extracted
5 studies · 5 participants
Low

Lifestyle interventions vs placebo or usual care

Weight loss (change in kg weight) · weight reduction in obesity to improve survival in women with endometrial cancer

1 finding from 1 review

Interventions for weight reduction in obesity to improve survival in women with endometrial cancer 2023 · Cochrane Headline outcomes only
no estimate extracted
5 studies · 209 participants
Low

Lifestyle interventions vs placebo or usual care

Cardiovascular and metabolic event frequency (12 months) (Number of strokes, myocardial infarctions and hospitalisations for heart failure) · weight reduction in obesity to improve survival in women with endometrial cancer

Summary of findings table ‐ Lifestyle intervention showed no clear difference in cardiovascular and metabolic event frequency (6 months) compared with usual care compared to placebo (low certainty).

1 finding from 1 review

Interventions for weight reduction in obesity to improve survival in women with endometrial cancer 2023 · Cochrane Headline outcomes only
RR 3.47 [0.15, 82.21]
5 studies · 211 participants
Low

Lifestyle interventions vs placebo or usual care

Quality of life: FACT‐G (12 months) · weight reduction in obesity to improve survival in women with endometrial cancer

1 finding from 1 review

Interventions for weight reduction in obesity to improve survival in women with endometrial cancer 2023 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 89 participants
Very low