Findings

What do systematic reviews say?

6 questions · 6 findings · 1 reviews

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No studies found 0 · 0%GRADE not reported 0 · 0%Very low 0 · 0%Low 4 · 66.7%Moderate 2 · 33.3%High 0 · 0%

HFNC vs standard oxygen therapy

Length of hospital stay · infants with bronchiolitis

1 finding from 1 review

High‐flow nasal cannula therapy for infants with bronchiolitis 2024 · Cochrane Headline outcomes only
no estimate extracted
7 studies · 1951 participants
Low

HFNC vs standard oxygen therapy

Adverse events · infants with bronchiolitis

Summary of findings table ‐ High‐flow nasal cannula showed no clear difference in adverse events compared with standard oxygen therapy (low‐flow) (low certainty).

1 finding from 1 review

High‐flow nasal cannula therapy for infants with bronchiolitis 2024 · Cochrane Headline outcomes only
RR 1.2 [0.38, 3.74]
4 studies · 1789 participants
Low

HFNC vs standard oxygen therapy

Change in respiratory rate at 20 minutes · infants with bronchiolitis

1 finding from 1 review

High‐flow nasal cannula therapy for infants with bronchiolitis 2024 · Cochrane Headline outcomes only
no estimate extracted
5 studies · 692 participants
Low

HFNC vs standard oxygen therapy

Change** in heart rate (beats/min) · infants with bronchiolitis

1 finding from 1 review

High‐flow nasal cannula therapy for infants with bronchiolitis 2024 · Cochrane Headline outcomes only
no estimate extracted
5 studies · 692 participants
Moderate

HFNC vs standard oxygen therapy

Need for treatment escalation · infants with bronchiolitis

Summary of findings table ‐ High‐flow nasal cannula probably leads to lower need for treatment escalation compared with standard oxygen therapy (low‐flow) (moderate certainty).

1 finding from 1 review

High‐flow nasal cannula therapy for infants with bronchiolitis 2024 · Cochrane Headline outcomes only
RR 0.55 [0.39, 0.79]
8 studies · 2215 participants
Moderate

HFNC vs standard oxygen therapy

Duration of oxygen therapy (hours) · infants with bronchiolitis

1 finding from 1 review

High‐flow nasal cannula therapy for infants with bronchiolitis 2024 · Cochrane Headline outcomes only
no estimate extracted
7 studies · 2132 participants
Low