Findings

What do systematic reviews say?

4 questions · 4 findings · 1 reviews

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No studies found 0 · 0%GRADE not reported 0 · 0%Very low 4 · 100%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

Metformin vs sulphonylureas

Cardiovascular mortality

1 finding from 1 review

Metformin monotherapy for adults with type 2 diabetes mellitus 2020 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 2940 participants
Very low

Metformin vs thiazolidinediones

Cardiovascular mortality

It is very uncertain whether summary of findings of metformin monotherapy for adults with type 2… changes cardiovascular mortality (CVM) compared with thiazolidinediones (very low certainty).

1 finding from 1 review

Metformin monotherapy for adults with type 2 diabetes mellitus 2020 · Cochrane Headline outcomes only
RR 0.71 [0.21, 2.39]
4 studies · 3211 participants
Very low

Metformin vs dipeptidyl‐peptidase 4 inhibitors

Cardiovascular mortality

1 finding from 1 review

Metformin monotherapy for adults with type 2 diabetes mellitus 2020 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 1206 participants
Very low

Metformin vs glucagon like peptide‐1 analogues

Cardiovascular mortality

1 finding from 1 review

Metformin monotherapy for adults with type 2 diabetes mellitus 2020 · Cochrane Headline outcomes only
no estimate extracted
1 study · 807 participants
Very low