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What do systematic reviews say?

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Evidence found and GRADE certainty

3 questions · 3 findings · 1 reviews

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No studies found 0 · 0%GRADE not reported 0 · 0%Very low 0 · 0%Low 0 · 0%Moderate 2 · 66.7%High 1 · 33.3%

Imiquimod vs placebo

Response to treatment at 12 months ‐ overall response · women with usual‐type vulval intraepithelial neoplasia

Summary of findings for imiquimod probably leads to higher response to treatment at 12 months ‐ overall response compared with placebo (moderate certainty).

1 finding from 1 review

Imiquimod vs cidofovir

Response to treatment at 6 months ‐ overall response · women with usual‐type vulval intraepithelial neoplasia

Summary of findings for imiquimod showed no clear difference in response to treatment at 6 months ‐ overall response compared with cidofovir (moderate certainty).

1 finding from 1 review

Imiquimod vs placebo

Response to treatment at 5 to 6 months ‐ overall response · women with usual‐type vulval intraepithelial neoplasia

Summary of findings for imiquimod leads to higher response to treatment at 5 to 6 months ‐ overall response compared with placebo (high certainty).

1 finding from 1 review