Findings

What do systematic reviews say?

2 questions · 2 findings · 1 reviews

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No studies found 0 · 0%GRADE not reported 0 · 0%Very low 0 · 0%Low 1 · 50%Moderate 1 · 50%High 0 · 0%

Summary of findings ‐ Intranasal midazolam vs intravenous diazepam

Seizure freedom · Children with acute tonic‐clonic seizures

Summary of findings ‐ Intranasal midazolam showed no clear difference in seizure cessation compared with intravenous diazepam (moderate certainty).

1 finding from 1 review

Drug management for acute tonic‐clonic convulsions including convulsive status epilepticus in children 2018 · Cochrane Headline outcomes only
RR 0.98 [0.91, 1.06]
2 studies · 122 participants
Moderate

Summary of findings ‐ Intranasal midazolam vs rectal diazepam

Seizure cessation: within 10 minutes · Children with acute tonic‐clonic seizures

Summary of findings ‐ Intranasal midazolam showed no clear difference in seizure cessation: within 10 minutes compared with rectal diazepam (low certainty).

1 finding from 1 review

Drug management for acute tonic‐clonic convulsions including convulsive status epilepticus in children 2018 · Cochrane Headline outcomes only
RR 1.47 [1, 2.16]
1 study · 45 participants
Low