Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

6 questions · 6 findings · 1 reviews

No studies found 1 · 16.7%GRADE not reported 0 · 0%Very low 5 · 83.3%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

Summary of findings ‐ Inhaled mannitol plus dornase alfa vs dornase alfa

Lung function: FEV1 mL (percentage change from baseline) · children and young adults with CF

It is very uncertain whether summary of findings ‐ Inhaled mannitol plus dornase alfa changes lung function: FEV1mL (percentage change from baseline) compared with dornase alfa (very low certainty).

1 finding from 1 review

Summary of findings ‐ Inhaled mannitol plus dornase alfa vs dornase alfa

Lung function: FEF25‐75 mL/s (percentage change from baseline) · children and young adults with CF

It is very uncertain whether summary of findings ‐ Inhaled mannitol plus dornase alfa changes lung function: FEF25-75 mL/s (percentage change from baseline) compared with dornase alfa (very low certainty).

1 finding from 1 review