What do systematic reviews say?

Summary of findings ‐ Buccal midazolam vs rectal diazepam

Summary of findings ‐ Buccal midazolam showed no clear difference in incidence of respiratory depression compared with rectal diazepam (low certainty).

• Drug management for acute tonic‐clonic convulsions including convulsive status epilepticus in children 2018 · Cochrane Headline outcomes only
  RR 0.88 [0.61, 1.25]
  4 studies · 648 participants
  Low

Summary of findings ‐ Buccal midazolam vs intravenous diazepam

• Drug management for acute tonic‐clonic convulsions including convulsive status epilepticus in children 2018 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 120 participants
  High