Findings

What do systematic reviews say?

4 questions · 5 findings · 1 reviews · Pain, Palliative and Supportive Care

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No studies found 1 · 20%GRADE not reported 0 · 0%Very low 0 · 0%Low 4 · 80%Moderate 0 · 0%High 0 · 0%

RISPERIDONE vs placebo

Symptoms of delirium within 24 hoursa · terminally ill adults with delirium

Summary of findings: risperidone showed no clear difference in symptoms of delirium within 24 hoursa compared with placebo (low certainty).

1 finding from 1 review

Drug therapy for delirium in terminally ill adults 2020 · Cochrane Headline outcomes only
MD 0.76
1 study · 129 participants
Low

RISPERIDONE vs placebo

Symptoms of delirium between 24 and 48 hoursa · terminally ill adults with delirium

Summary of findings: risperidone showed no clear difference in symptoms of delirium between 24 and 48 hoursa compared with placebo (low certainty).

1 finding from 1 review

Drug therapy for delirium in terminally ill adults 2020 · Cochrane Headline outcomes only
MD 0.85
1 study · 111 participants
Low

RISPERIDONE vs placebo

Specific behaviour ‐ agitation · terminally ill adults with delirium

The review found no eligible studies for this question.

2 findings from 1 review

Drug therapy for delirium in terminally ill adults 2020 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found
Drug therapy for delirium in terminally ill adults 2020 · Cochrane Headline outcomes only
no estimate extracted
1 study · 111 participants
Low

RISPERIDONE vs placebo

Adverse events including extrapyramidal effects · terminally ill adults with delirium

Summary of findings: risperidone showed no clear difference in adverse events including extrapyramidal effectsd compared with placebo (low certainty).

1 finding from 1 review

Drug therapy for delirium in terminally ill adults 2020 · Cochrane Headline outcomes only
MD 0.73
1 study · 111 participants
Low