What do systematic reviews say?

Summary of findings: punctal plugs vs no punctal plugs

• Punctal occlusion for dry eye syndrome 2017 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 89 participants
  Very low

Summary of findings: punctal plugs vs pilocarpine

It is very uncertain whether summary of findings: punctal plugs changes symptomatic improvement compared with oral pilocarpine (very low certainty).

• Punctal occlusion for dry eye syndrome 2017 · Cochrane Headline outcomes only
  RR 0.69 [0.49, 0.95]
  Studies not reported
  Very low

Summary of findings: punctal plugs vs artificial tears

It is very uncertain whether summary of findings: punctal plugs changes symptomatic improvement compared with artificial tears (very low certainty).

• Punctal occlusion for dry eye syndrome 2017 · Cochrane Headline outcomes only
  RR 2.29 [1.2, 4.38]
  Studies not reported
  Very low

Summary of findings: punctal plugs vs cyclosporine A

• Punctal occlusion for dry eye syndrome 2017 · Cochrane Headline outcomes only
  no estimate extracted
  2 participants
  GRADE not reported

Summary of findings: punctal plugs in the upper vs lower puncta

The review found no eligible studies for this question.

• Punctal occlusion for dry eye syndrome 2017 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found