Summary of findings: needle acupuncture vs sham
Seizure frequency reduction (3‐month blinded evaluation period) · adults with intractable epilepsy
1 finding from 1 review
- no estimate extracted1 study · 34 participantsLow
Findings
What do systematic reviews say?
22 questions · 22 findings · 1 reviews
No studies found 0 · 0%GRADE not reported 3 · 13.6%Very low 0 · 0%Low 17 · 77.3%Moderate 2 · 9.1%High 0 · 0%
Summary of findings: needle acupuncture vs sham
Quality of life (QOLIE‐89) (1‐ to 3‐month periods) · adults with intractable epilepsy
1 finding from 1 review
- no estimate extracted1 study · 22 participantsLow
Summary of findings: needle acupuncture vs sham
Lack of efficacy withdrawal · adults with intractable epilepsy
Summary of findings: needle acupuncture showed no clear difference in withdrawal due to lack of efficacy ( compared with sham acupuncture (low certainty).
1 finding from 1 review
- RR 1.33 [0.25, 7]1 study · 34 participantsLow
Summary of findings: needle acupuncture vs sham
Adverse effects ( · adults with intractable epilepsy
1 finding from 1 review
- no estimate extracted2 studies · 120 participantsGRADE not reported
Summary of findings: needle acupuncture vs phenytoin
50% or greater reduction in seizure frequency · people with epilepsy
Summary of findings: needle acupuncture showed no clear difference in 50% or greater reduction in seizure frequency ( compared with phenytoin (low certainty).
1 finding from 1 review
- RR 1.43 [0.46, 4.44]2 studies · 150 participantsLow
Summary of findings: needle acupuncture vs phenytoin
Adverse effects ( · people with epilepsy
1 finding from 1 review
- no estimate extracted2 studies · 120 participantsGRADE not reported
Summary of findings: needle acupuncture vs valproate
Seizure freedom · participants with epilepsy (one included study only recruited children with absence epilepsy while another included study recruited both…
Summary of findings: needle acupuncture showed no clear difference in seizure freedom ( compared with valproate (low certainty).
1 finding from 1 review
- RR 1.75 [0.93, 3.27]2 studies · 180 participantsLow
Summary of findings: needle acupuncture vs valproate
50% or greater reduction in seizure frequency · participants with epilepsy (one included study only recruited children with absence epilepsy while another included study recruited both…
Summary of findings: needle acupuncture may leads to higher 50% or greater reduction in seizure frequency ( compared with valproate (low certainty).
1 finding from 1 review
- RR 1.32 [1.05, 1.66]2 studies · 180 participantsLow
Summary of findings: needle acupuncture vs valproate
Post‐treatment quality of life (QOLIE‐31 score, which has a range of 0‐200, with higher score indicates better quality of life) ( · participants with epilepsy (one included study only recruited children with absence epilepsy while another included study recruited both…
1 finding from 1 review
- no estimate extracted1 study · 100 participantsLow
Summary of findings: needle acupuncture vs valproate
Frequency of adverse effects ‐ dizziness ( · participants with epilepsy (one included study only recruited children with absence epilepsy while another included study recruited both…
Summary of findings: needle acupuncture showed no clear difference in frequency of adverse effects ‐ dizziness ( compared with valproate (low certainty).
1 finding from 1 review
- RR 1.13 [0.47, 2.68]1 study · 100 participantsLow
Summary of findings: needle acupuncture vs valproate
Frequency of adverse effects ‐ malaise ( · participants with epilepsy (one included study only recruited children with absence epilepsy while another included study recruited both…
Summary of findings: needle acupuncture showed no clear difference in frequency of adverse effects ‐ malaise ( compared with valproate (low certainty).
1 finding from 1 review
- RR 0.69 [0.33, 1.47]1 study · 100 participantsLow
Summary of findings: needle acupuncture vs valproate
Nausea · participants with epilepsy (one included study only recruited children with absence epilepsy while another included study recruited both…
Summary of findings: needle acupuncture showed no clear difference in frequency of adverse effects ‐ nausea ( compared with valproate (low certainty).
1 finding from 1 review
- RR 0.14 [0.02, 1.12]1 study · 100 participantsLow
Summary of findings: needle acupuncture vs valproate
Frequency of adverse effects ‐ sleepiness ( · participants with epilepsy (one included study only recruited children with absence epilepsy while another included study recruited both…
Summary of findings: needle acupuncture showed no clear difference in frequency of adverse effects ‐ sleepiness ( compared with valproate (low certainty).
1 finding from 1 review
- RR 0.6 [0.15, 2.38]1 study · 100 participantsLow
Summary of findings: needle acupuncture plus valproate vs valproate
Seizure freedom · participants with generalised epilepsy
Summary of findings: needle acupuncture plus valproate showed no clear difference in seizure freedom ( compared with valproate alone (moderate certainty).
1 finding from 1 review
- RR 0.97 [0.72, 1.3]2 studies · 150 participantsModerate
Summary of findings: needle acupuncture plus valproate vs valproate
50% or greater reduction in seizure frequency · participants with generalised epilepsy
Summary of findings: needle acupuncture plus valproate showed no clear difference in 50% or greater reduction in seizure frequency ( compared with valproate alone (low certainty).
1 finding from 1 review
- RR 1.34 [0.52, 3.48]2 studies · 150 participantsLow
Summary of findings: needle acupuncture plus valproate vs valproate
Post‐treatment quality of life (QOLIE‐31 score, which has a range of 0‐200, with higher score indicates better quality of life) ( · participants with generalised epilepsy
1 finding from 1 review
- no estimate extracted1 study · 90 participantsLow
Summary of findings: needle acupuncture plus valproate vs valproate
Frequency of adverse effects ‐ dizziness ( · participants with generalised epilepsy
Summary of findings: needle acupuncture plus valproate showed no clear difference in frequency of adverse effects ‐ dizziness ( compared with valproate alone (low certainty).
1 finding from 1 review
- RR 0.67 [0.12, 3.8]1 study · 90 participantsLow
Summary of findings: needle acupuncture plus valproate vs valproate
Frequency of adverse effects ‐ malaise ( · participants with generalised epilepsy
Summary of findings: needle acupuncture plus valproate showed no clear difference in frequency of adverse effects ‐ malaise ( compared with valproate alone (low certainty).
1 finding from 1 review
- RR 0.83 [0.27, 2.54]1 study · 90 participantsLow
Summary of findings: needle acupuncture plus valproate vs valproate
Nausea · participants with generalised epilepsy
Summary of findings: needle acupuncture plus valproate showed no clear difference in frequency of adverse effects ‐ nausea ( compared with valproate alone (low certainty).
1 finding from 1 review
- RR 0.6 [0.15, 2.36]1 study · 90 participantsLow
Summary of findings: needle acupuncture plus valproate vs valproate
Frequency of adverse effects ‐ sleepiness ( · participants with generalised epilepsy
Summary of findings: needle acupuncture plus valproate showed no clear difference in frequency of adverse effects ‐ sleepiness ( compared with valproate alone (low certainty).
1 finding from 1 review
- RR 0.71 [0.24, 2.08]1 study · 90 participantsLow