What do systematic reviews say?

Tranexamic acid vs placebo

The review found no eligible studies for this question.

• Drugs to reduce bleeding and transfusion in major open vascular or endovascular surgery: a systematic review and… 2023 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Tranexamic acid vs placebo

• Drugs to reduce bleeding and transfusion in major open vascular or endovascular surgery: a systematic review and… 2023 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 100 participants
  Very low

Tranexamic acid vs placebo

It is very uncertain whether summary of findings: Tranexamic acid changes risk of receiving any allogeneic blood product (data only available… compared with placebo (very low certainty).

• Drugs to reduce bleeding and transfusion in major open vascular or endovascular surgery: a systematic review and… 2023 · Cochrane Headline outcomes only
  RR 0.66 [0.11, 3.95]
  1 study · 100 participants
  Very low

Tranexamic acid vs placebo

It is very uncertain whether summary of findings: Tranexamic acid changes risk of reoperation or repeat procedure for bleeding within 7 days compared with placebo (very low certainty).

• Drugs to reduce bleeding and transfusion in major open vascular or endovascular surgery: a systematic review and… 2023 · Cochrane Headline outcomes only
  RR 0.33 [0.01, 7.99]
  1 study · 100 participants
  Very low

Tranexamic acid vs placebo

Summary of findings: Tranexamic acid showed no clear difference in risk of a thrombotic/thromboembolic event (MI, CVA, DVT, PE) compared with placebo (low certainty).

• Drugs to reduce bleeding and transfusion in major open vascular or endovascular surgery: a systematic review and… 2023 · Cochrane Headline outcomes only
  RR 1.1 [0.88, 1.36]
  1 study · 1360 participants
  Low