Findings

What do systematic reviews say?

5 questions · 5 findings · 1 reviews

No studies found 0 · 0%GRADE not reported 0 · 0%Very low 0 · 0%Low 0 · 0%Moderate 2 · 40%High 3 · 60%

Death from all causes · women with stage I endometrial cancer

Summary of findings: EBRT showed no clear difference in death from all causes compared with no EBRT (moderate certainty).

1 finding from 1 review

Adjuvant radiotherapy for stage I endometrial cancer 2012 · Cochrane Headline outcomes only
HR 0.99 [0.82, 1.2]
2628 participants
Moderate

Endometrial carcinoma‐related death · women with stage I endometrial cancer

Summary of findings: EBRT showed no clear difference in endometrial carcinoma‐related death compared with no EBRT (moderate certainty).

1 finding from 1 review

Adjuvant radiotherapy for stage I endometrial cancer 2012 · Cochrane Headline outcomes only
HR 0.96 [0.72, 1.28]
2965 participants
Moderate

Locoregional recurrence · women with stage I endometrial cancer

Summary of findings: EBRT leads to lower locoregional recurrence compared with no EBRT (high certainty).

1 finding from 1 review

Adjuvant radiotherapy for stage I endometrial cancer 2012 · Cochrane Headline outcomes only
HR 0.36 [0.25, 0.52]
2965 participants
High

Severe acute toxicity · women with stage I endometrial cancer

Summary of findings: EBRT leads to higher severe acute toxicity compared with no EBRT (high certainty).

1 finding from 1 review

Adjuvant radiotherapy for stage I endometrial cancer 2012 · Cochrane Headline outcomes only
RR 4.68 [1.35, 16.16]
1328 participants
High

Severe late toxicity · women with stage I endometrial cancer

Summary of findings: EBRT leads to higher severe late toxicity compared with no EBRT (high certainty).

1 finding from 1 review

Adjuvant radiotherapy for stage I endometrial cancer 2012 · Cochrane Headline outcomes only
RR 2.58 [1.61, 4.11]
3501 participants
High