What do systematic reviews say?

Summary of findings: EBRT vs no EBRT

Summary of findings: EBRT showed no clear difference in death from all causes compared with no EBRT (moderate certainty).

• Adjuvant radiotherapy for stage I endometrial cancer 2012 · Cochrane Headline outcomes only
  HR 0.99 [0.82, 1.2]
  2628 participants
  Moderate

Summary of findings: EBRT vs no EBRT

Summary of findings: EBRT showed no clear difference in endometrial carcinoma‐related death compared with no EBRT (moderate certainty).

• Adjuvant radiotherapy for stage I endometrial cancer 2012 · Cochrane Headline outcomes only
  HR 0.96 [0.72, 1.28]
  2965 participants
  Moderate

Summary of findings: EBRT vs no EBRT

Summary of findings: EBRT leads to lower locoregional recurrence compared with no EBRT (high certainty).

• Adjuvant radiotherapy for stage I endometrial cancer 2012 · Cochrane Headline outcomes only
  HR 0.36 [0.25, 0.52]
  2965 participants
  High

Summary of findings: EBRT vs no EBRT

Summary of findings: EBRT leads to higher severe acute toxicity compared with no EBRT (high certainty).

• Adjuvant radiotherapy for stage I endometrial cancer 2012 · Cochrane Headline outcomes only
  RR 4.68 [1.35, 16.16]
  1328 participants
  High

Summary of findings: EBRT vs no EBRT

Summary of findings: EBRT leads to higher severe late toxicity compared with no EBRT (high certainty).

• Adjuvant radiotherapy for stage I endometrial cancer 2012 · Cochrane Headline outcomes only
  RR 2.58 [1.61, 4.11]
  3501 participants
  High

Summary of findings: BT vs external beam radiotherapy (EBRT)

The review found no eligible studies for this question.

• Interventions to reduce acute and late adverse gastrointestinal effects of pelvic radiotherapy for primary pelvic… 2018 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Summary of findings: BT vs external beam radiotherapy (EBRT)

• Interventions to reduce acute and late adverse gastrointestinal effects of pelvic radiotherapy for primary pelvic… 2018 · Cochrane Headline outcomes only
  no estimate extracted
  0 participants
  GRADE not reported

Summary of findings: BT vs external beam radiotherapy (EBRT)

• Interventions to reduce acute and late adverse gastrointestinal effects of pelvic radiotherapy for primary pelvic… 2018 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 348 participants
  GRADE not reported

Summary of findings: BT vs external beam radiotherapy (EBRT)

• Interventions to reduce acute and late adverse gastrointestinal effects of pelvic radiotherapy for primary pelvic… 2018 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 348 participants
  GRADE not reported