Findings

What do systematic reviews say?

4 questions · 4 findings · 1 reviews

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No studies found 0 · 0%GRADE not reported 0 · 0%Very low 1 · 25%Low 3 · 75%Moderate 0 · 0%High 0 · 0%

Sublingual misoprostol vs vaginal misoprostol

Failure to achieve complete abortion · first trimester abortion

Sublingual misoprostol alone showed no clear difference in failure to achieve complete abortion compared with vaginal misoprostol alone (low certainty).

1 finding from 1 review

Medical methods for first trimester abortion 2022 · Cochrane Headline outcomes only
RR 0.69 [0.37, 1.28]
5 studies · 2705 participants
Low

Sublingual misoprostol vs vaginal misoprostol

Nausea · first trimester abortion

Sublingual misoprostol alone showed no clear difference in nausea compared with vaginal misoprostol alone (low certainty).

1 finding from 1 review

Medical methods for first trimester abortion 2022 · Cochrane Headline outcomes only
RR 1.61 [0.78, 3.33]
4 studies · 2505 participants
Low

Sublingual misoprostol vs vaginal misoprostol

Women's dissatisfaction with the procedure · first trimester abortion

Sublingual misoprostol alone may leads to lower women's dissatisfaction with the procedure compared with vaginal misoprostol alone (low certainty).

1 finding from 1 review

Medical methods for first trimester abortion 2022 · Cochrane Headline outcomes only
RR 0.14 [0.07, 0.29]
1 study · 220 participants
Low

Sublingual misoprostol vs vaginal misoprostol

Blood transfusion · first trimester abortion

It is very uncertain whether sublingual misoprostol alone changes blood transfusion compared with vaginal misoprostol alone (very low certainty).

1 finding from 1 review

Medical methods for first trimester abortion 2022 · Cochrane Headline outcomes only
RR 5 [0.24, 102.96]
1 study · 220 participants
Very low