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Evidence found and GRADE certainty

6 questions · 6 findings · 1 reviews · Cystic Fibrosis and Genetic Disorders

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No studies found 2 · 33.3%GRADE not reported 0 · 0%Very low 3 · 50%Low 1 · 16.7%Moderate 0 · 0%High 0 · 0%

Statins with cholesterol supplementation vs cholesterol supplementation only

Statin‐related adverse events · children and adults with Smith‐Lemli‐Opitz syndrome

It is very uncertain whether statins with cholesterol supplementation changes statin‐related adverse events compared with cholesterol supplementation only (very low certainty).

1 finding from 1 review

Statins with cholesterol supplementation vs cholesterol supplementation only

Changes in biochemical markers plasma dehydrocholesterol levels (mM); plasma cholesterol levels (mM); plasma 7DHC levels (mM); plasma CoQ levels (uM); CSF cholesterol levels (ug/mL); CSF dehydrocholesterol levels (ug/mL) · children and adults with Smith‐Lemli‐Opitz syndrome
1 finding from 1 review