Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

8 questions · 8 findings · 1 reviews · Headline outcomes only

No studies found 1 · 12.5%GRADE not reported 1 · 12.5%Very low 0 · 0%Low 2 · 25%Moderate 4 · 50%High 0 · 0%

Standard testing plus PET/CT scanning vs standard testing alone

Cancer‐related mortality at maximal · people with unprovoked VTE

Standard testing plus PET/CT scanning showed no clear difference in cancer‐related mortality3 compared with standard testing alone (moderate certainty).

1 finding from 1 review

Standard testing plus PET/CT scanning vs standard testing alone

VTE‐related morbidity5 · people with unprovoked VTE

Standard testing plus PET/CT scanning showed no clear difference in VTE‐related morbidity5 compared with standard testing alone (moderate certainty).

1 finding from 1 review

Standard testing plus PET/CT scanning vs standard testing alone

Stage at diagnosis (early-stage detection) · people with unprovoked VTE

Standard testing plus PET/CT scanning showed no clear difference in stage of cancer ‐ early compared with standard testing alone (low certainty).

1 finding from 1 review

Standard testing plus PET/CT scanning vs standard testing alone

Stage of cancer ‐ advanced · people with unprovoked VTE

Standard testing plus PET/CT scanning showed no clear difference in stage of cancer ‐ advanced compared with standard testing alone (low certainty).

1 finding from 1 review

Standard testing plus PET/CT scanning vs standard testing alone

Frequency of an underlying cancer diagnosis8 · people with unprovoked VTE

Standard testing plus PET/CT scanning showed no clear difference in frequency of an underlying cancer diagnosis8 compared with standard testing alone (moderate certainty).

1 finding from 1 review

Standard testing plus PET/CT scanning vs standard testing alone

All‐cause mortality1 · people with unprovoked VTE

Standard testing plus PET/CT scanning showed no clear difference in all‐cause mortality1 compared with standard testing alone (moderate certainty).

1 finding from 1 review