Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

13 questions · 13 findings · 2 reviews · Kidney and Transplant

No studies found 7 · 53.8%GRADE not reported 0 · 0%Very low 0 · 0%Low 2 · 15.4%Moderate 4 · 30.8%High 0 · 0%

Aldosterone antagonists vs placebo or usual care

All cardiovascular death · people with chronic kidney disease requiring dialysis

Aldosterone antagonists (spironolactone or eplerenone) probably leads to lower death (cardiovascular) compared with control (placebo or standard care) (moderate certainty).

1 finding from 1 review

Aldosterone antagonists vs placebo or usual care

Cardiovascular and cerebrovascular morbidity · people with chronic kidney disease requiring dialysis

Aldosterone antagonists (spironolactone or eplerenone) probably leads to lower cardiovascular and cerebrovascular morbidity compared with control (placebo or standard care) (moderate certainty).

1 finding from 1 review