Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

17 questions · 18 findings · 4 reviews · Headline outcomes only

No studies found 1 · 5.6%GRADE not reported 0 · 0%Very low 5 · 27.8%Low 10 · 55.6%Moderate 2 · 11.1%High 0 · 0%

Slow vs faster rates of enteral feed advancement

Necrotising enterocolitis · very preterm or very low birth weight infants

Slow showed no clear difference in necrotising enterocolitis before hospital discharge compared with faster rates of enteral feed advancement (moderate certainty).

1 finding from 1 review

Slow vs faster rates of enteral feed advancement

Mortality before hospital discharge · very preterm or very low birth weight infants

Slow showed no clear difference in mortality before hospital discharge compared with faster rates of enteral feed advancement (moderate certainty).

1 finding from 1 review

Slow vs faster rates of enteral feed advancement

Invasive infection (before hospital discharge) · very preterm or very low birth weight infants

Slow showed no clear difference in invasive infection before hospital discharge compared with faster rates of enteral feed advancement (low certainty).

1 finding from 1 review

Slow vs fast subcutaneous heparin injection

Bruise incidence ‐ 48 hours after injection · patients treated with subcutaneous heparin injections

Slow may leads to lower bruise incidence ‐ 48 hours after injection compared with fast subcutaneous heparin injection (low certainty).

2 findings from 1 review

Slow passive expiration vs control

Change in the severity status of bronchiolitis Assessed using a variety of scales · infants up to 24 months of age with acute bronchiolitis

Slow passive expiration showed no clear difference in change in the severity status of bronchiolitis Assessed using a… compared with control (low certainty).

1 finding from 1 review