Primary caries prevention · Children and adults (with or without carious lesions)
It is very uncertain whether silver diamine fluoride (SDF) changes primary caries prevention compared with placebo or no treatment (very low certainty).
3 findings from 1 review
MD -1.14 [-1.58, -0.70]
1 study · 373 participants
Very low
MD -0.79 [-1.40, -0.17]
3 studies · 439 participants
Moderate
MD -0.69 [-0.97, -0.41]
1 study · 373 participants
Very low
Secondary prevention of caries · Children and adults (with or without carious lesions)
The review found no eligible studies for this question.
3 findings from 1 review
No studies reported data in this dentition type
0 studies
No studies found
MD 0.04 [-0.30, 0.38]
1 study · 309 participants
Very low
No studies reported data in this dentition type
0 studies
No studies found
Caries arrest · Children and adults (with or without carious lesions)
It is very uncertain whether silver diamine fluoride (SDF) changes caries arrest compared with restoration (restorative treatment) (very low certainty).
1 finding from 1 review
Primary caries prevention · Children and adults (with or without carious lesions)
The review found no eligible studies for this question.
1 finding from 1 review
Primary caries prevention · Children and adults (with or without carious lesions)
It is very uncertain whether silver diamine fluoride (SDF) changes primary caries prevention compared with chlorhexidine varnish (very low certainty).
1 finding from 1 review
Secondary prevention of caries · Children and adults (with or without carious lesions)
The review found no eligible studies for this question.
1 finding from 1 review
Dental pain or sensitivity · Children and adults (with or without carious lesions)
It is very uncertain whether silver diamine fluoride (SDF) changes dental pain or sensitivity compared with restoration (restorative treatment) (very low certainty).
1 finding from 1 review
Secondary prevention of caries · Children and adults (with or without carious lesions)
The review found no eligible studies for this question.
1 finding from 1 review
Caries arrest · Children and adults (with or without carious lesions)
It is very uncertain whether silver diamine fluoride (SDF) changes caries arrest compared with glass ionomer cement (GIC) plus fluoride varnish (very low certainty).
1 finding from 1 review
Caries arrest · Children and adults (with or without carious lesions)
The review found no eligible studies for this question.
3 findings from 1 review
No studies reported data in this dentition type
0 studies
No studies found
No studies reported data in this dentition type
0 studies
No studies found
MD -0.13 [-0.87, 0.61]
1 study · 309 participants
Very low
Caries arrest · Children and adults (with or without carious lesions)
Silver diamine fluoride (SDF) showed no clear difference in caries arrest compared with silver nitrate plus fluoride varnish (low certainty).
1 finding from 1 review
Dental pain or sensitivity · Children and adults (with or without carious lesions)
The review found no eligible studies for this question.
1 finding from 1 review
Dental pain or sensitivity · Children and adults (with or without carious lesions)
The review found no eligible studies for this question.
1 finding from 1 review
Primary caries prevention · Children and adults (with or without carious lesions)
The review found no eligible studies for this question.
1 finding from 1 review
Dental pain or sensitivity · Children and adults (with or without carious lesions)
The review found no eligible studies for this question.
1 finding from 1 review
Secondary caries prevention in young permanent first molars · Children with deep occlusal caries in young permanent first molars (indirect pulp capping)
SDF and RMGIC did not differ significantly for secondary caries prevention in young permanent molars (no events; p>0.05; ungraded).
1 finding from 1 review
Baraka et al. (2022): no significant difference in secondary caries prevention between 38% SDF and RMGIC (no secondary caries in either group through 12 months; p=0.63 at 12 months; overall p=0.26).
1 study · 49 participants
GRADE not reported
Secondary caries prevention in young permanent first molars · Children with deep occlusal caries in young permanent first molars (indirect pulp capping)
SDF+KI and RMGIC did not differ significantly for secondary caries prevention (p>0.05; ungraded).
1 finding from 1 review
Inactive (arrested) carious lesions on permanent first molars · Children with dental caries in permanent (first) molars
Six-monthly SDF produced significantly more inactive (arrested) lesions than no treatment in children's permanent molars (0.3 vs 0.1; p<0.05; ungraded).
1 finding from 1 review
Caries arrest · Children and adults (with or without carious lesions)
1 finding from 1 review
In 1 study (45 children), 4 applications of 38% SDF at 1-monthly intervals resulted in fewer surfaces with active caries compared with 2 applications at 6-monthly intervals (MD 1.04 surfaces, 95% CI 0.23 to 1.85), and…
4 studies · 1360 participants
Very low
Secondary prevention of caries · Children and adults (with or without carious lesions)
It is very uncertain whether SDF (given at a particular frequency, concentration, or duration) changes secondary prevention of caries compared with SDF (given at a different frequency, concentration, or duration) (very low certainty).
1 finding from 1 review