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What do systematic reviews say?

4 questions · 8 findings · 2 reviews · asked by two or more reviews

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No studies found 2 · 25%GRADE not reported 0 · 0%Very low 2 · 25%Low 3 · 37.5%Moderate 1 · 12.5%High 0 · 0%

Short‐acting insulin analogues vs regular human insulin

All‐cause mortality

Short‐acting insulin analogues showed no clear difference in all‐cause mortality (N) compared with regular human insulin (moderate certainty).

2 findings from 2 reviews · compare the 2 reviews

Short‐acting insulin analogues versus regular human insulin for adult, non‐pregnant persons with type 2 diabetes… 2018 · Cochrane Headline outcomes only
Peto OR 1.66 [0.41, 6.64]
6 studies · 2519 participants
Moderate
Short‐acting insulin analogues versus regular human insulin for adults with type 1 diabetes mellitus 2016 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Short‐acting insulin analogues vs regular human insulin

Severe hypoglycaemia

2 findings from 2 reviews · compare the 2 reviews

Short‐acting insulin analogues versus regular human insulin for adult, non‐pregnant persons with type 2 diabetes… 2018 · Cochrane Headline outcomes only
no estimate extracted
6 studies · 2509 participants
Low
Short‐acting insulin analogues versus regular human insulin for adults with type 1 diabetes mellitus 2016 · Cochrane Headline outcomes only
OR 0.89 [0.71, 1.12]
7 studies · 2459 participants
Very low

Short‐acting insulin analogues vs regular human insulin

HbA1c (%)

2 findings from 2 reviews · compare the 2 reviews

Short‐acting insulin analogues versus regular human insulin for adult, non‐pregnant persons with type 2 diabetes… 2018 · Cochrane Headline outcomes only
no estimate extracted
9 studies · 2608 participants
Low
Short‐acting insulin analogues versus regular human insulin for adults with type 1 diabetes mellitus 2016 · Cochrane Headline outcomes only
no estimate extracted
9 studies · 2608 participants
Low

Short‐acting insulin analogues vs regular human insulin

Health‐related quality of life

2 findings from 2 reviews · compare the 2 reviews

Short‐acting insulin analogues versus regular human insulin for adult, non‐pregnant persons with type 2 diabetes… 2018 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 2 participants
Very low
Short‐acting insulin analogues versus regular human insulin for adults with type 1 diabetes mellitus 2016 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found