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Evidence found and GRADE certainty

6 questions · 6 findings · 1 reviews · Metabolic and Endocrine Disorders

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No studies found 3 · 50%GRADE not reported 0 · 0%Very low 0 · 0%Low 3 · 50%Moderate 0 · 0%High 0 · 0%

Selenium (+LT4) vs placebo (+LT4)

Change from baseline in assessment of symptoms such as mood, fatigue and muscle weakness Short‐Form Health Survey · participants with Hashimoto's thyroiditis.

Selenium (+LT4) may leads to higher change from baseline in assessment of symptoms such as mood, fatigue… compared with placebo (+LT4) (low certainty).

1 finding from 1 review

Selenium (+LT4) vs placebo (+LT4)

Adverse events post‐intervention Number of people reporting an adverse event before completing the intervention · participants with Hashimoto's thyroiditis.

Selenium (+LT4) showed no clear difference in proportion of participants reporting an adverse event compared with placebo (+LT4) (low certainty).

1 finding from 1 review