Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

25 questions · 26 findings · 5 reviews · Headline outcomes only

No studies found 1 · 3.8%GRADE not reported 3 · 11.5%Very low 15 · 57.7%Low 2 · 7.7%Moderate 5 · 19.2%High 0 · 0%

Selective serotonin reuptake inhibitors vs tricyclic antidepressants (TCAs)

Efficacy as a dichotomous outcome · patients with cancer and depression

It is very uncertain whether selective serotonin reuptake inhibitors (SSRIs) changes efficacy as a dichotomous outcome compared with tricyclic antidepressants (TCAs) (very low certainty).

1 finding from 1 review

Selective serotonin reuptake inhibitors vs tricyclic antidepressants (TCAs)

Acceptability ‐ total dropouts · patients with cancer and depression

It is very uncertain whether selective serotonin reuptake inhibitors (SSRIs) changes dropouts due to any cause (acceptability) compared with tricyclic antidepressants (TCAs) (very low certainty).

1 finding from 1 review