Findings

What do systematic reviews say?

2 questions · 2 findings · 1 reviews

No studies found 0 · 0%GRADE not reported 0 · 0%Very low 0 · 0%Low 0 · 0%Moderate 2 · 100%High 0 · 0%

Abnormal uterine bleeding: amenorrhoea · uterine fibroids

SPRM showed no clear difference in abnormal uterine bleeding: amenorrhoea compared with leuprolide acetate (moderate certainty).

1 finding from 1 review

Selective progesterone receptor modulators (SPRMs) for uterine fibroids 2017 · Cochrane Headline outcomes only
OR 1.14 [0.6, 2.16]
1 study · 280 participants
Moderate

Abnormal uterine bleeding: amenorrhoea · women with uterine fibroids

SPRM probably leads to higher abnormal uterine bleeding: amenorrhoea compared with placebo (moderate certainty).

1 finding from 1 review

Selective progesterone receptor modulators (SPRMs) for uterine fibroids 2017 · Cochrane Headline outcomes only
OR 82.5 [37.1, 183.9]
7 studies · 590 participants
Moderate