What do systematic reviews say?

6 questions · 6 findings · 1 reviews · Oral Health

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No studies found 2 · 33.3%GRADE not reported 0 · 0%Very low 4 · 66.7%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

SDF (given at a particular frequency, concentration, or duration) vs SDF (given at a different frequency, concentration, or duration)

Caries arrest · Children and adults (with or without carious lesions)

1 finding from 1 review

Topical silver diamine fluoride (SDF) for preventing and managing dental caries in children and adults 2024 · Cochrane All outcomes
12 to 30 months · Primary dentition
In 1 study (45 children), 4 applications of 38% SDF at 1-monthly intervals resulted in fewer surfaces with active caries compared with 2 applications at 6-monthly intervals (MD 1.04 surfaces, 95% CI 0.23 to 1.85), and…
4 studies · 1360 participants
Very low

SDF (given at a particular frequency, concentration, or duration) vs SDF (given at a different frequency, concentration, or duration)

Aesthetics · Children and adults (with or without carious lesions)

1 finding from 1 review

Topical silver diamine fluoride (SDF) for preventing and managing dental caries in children and adults 2024 · Cochrane All outcomes
24 months · Children
1 study (119 children) reported that 45% parents were satisfied with child's dental appearance (data not reported by study group)
1 study · 119 participants
Very low

SDF (given at a particular frequency, concentration, or duration) vs SDF (given at a different frequency, concentration, or duration)

Secondary prevention of caries · Children and adults (with or without carious lesions)

It is very uncertain whether SDF (given at a particular frequency, concentration, or duration) changes secondary prevention of caries compared with SDF (given at a different frequency, concentration, or duration) (very low certainty).

1 finding from 1 review

Topical silver diamine fluoride (SDF) for preventing and managing dental caries in children and adults 2024 · Cochrane All outcomes
30 months · Primary dentition
MD -0.10 [-0.61, 0.41]
1 study · 203 participants
Very low

SDF (given at a particular frequency, concentration, or duration) vs SDF (given at a different frequency, concentration, or duration)

Primary caries prevention · Children and adults (with or without carious lesions)

The review found no eligible studies for this question.

1 finding from 1 review

Topical silver diamine fluoride (SDF) for preventing and managing dental caries in children and adults 2024 · Cochrane All outcomes
No studies reported data for this outcome
0 studies
No studies found

SDF (given at a particular frequency, concentration, or duration) vs SDF (given at a different frequency, concentration, or duration)

Dental pain or sensitivity · Children and adults (with or without carious lesions)

The review found no eligible studies for this question.

1 finding from 1 review

Topical silver diamine fluoride (SDF) for preventing and managing dental caries in children and adults 2024 · Cochrane All outcomes
No studies reported data for this outcome
0 studies
No studies found

SDF (given at a particular frequency, concentration, or duration) vs SDF (given at a different frequency, concentration, or duration)

Adverse effects · Children and adults (with or without carious lesions)

1 finding from 1 review

Topical silver diamine fluoride (SDF) for preventing and managing dental caries in children and adults 2024 · Cochrane All outcomes
24 to 30 months · Children
1 study (203 children) reported that black or brown staining on treated lesions was commonly found in both groups, with little or no difference according to whether SDF treatment was given in 3 applications at…
3 studies · 1121 participants
Very low