Findings

What do systematic reviews say?

2 questions · 2 findings · 1 reviews

No studies found 1 · 50%GRADE not reported 0 · 0%Very low 0 · 0%Low 0 · 0%Moderate 0 · 0%High 1 · 50%

50% or greater reduction in seizure frequency · Lennox‐Gastaut syndrome, any age

Rufinamide plus ASMs leads to higher number of participants with ≥ 50% reduction in all seizures compared with placebo plus ASMs (high certainty).

1 finding from 1 review

Anti‐seizure medications for Lennox‐Gastaut syndrome 2021 · Cochrane Headline outcomes only
RR 2.84 [1.31, 6.18]
1 study · 138 participants
High

50% or greater reduction in seizure frequency · Lennox‐Gastaut syndrome, any age

The review found no eligible studies for this question.

1 finding from 1 review

Anti‐seizure medications for Lennox‐Gastaut syndrome 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found