Findings

What do systematic reviews say?

2 questions · 6 findings · 1 reviews

No studies found 0 · 0%GRADE not reported 0 · 0%Very low 2 · 33.3%Low 2 · 33.3%Moderate 1 · 16.7%High 1 · 16.7%

All serious adverse events · children

RotaTeq showed no clear difference in all serious adverse events compared with placebo (high certainty).

3 findings from 1 review

Vaccines for preventing rotavirus diarrhoea: vaccines in use 2021 · Cochrane Headline outcomes only
RR 0.92 [0.84, 1.01]
5 studies · 70690 participants
High
Vaccines for preventing rotavirus diarrhoea: vaccines in use 2021 · Cochrane Headline outcomes only
RR 0.66 [0.14, 3.17]
2 studies · 4082 participants
Very low
Vaccines for preventing rotavirus diarrhoea: vaccines in use 2021 · Cochrane Headline outcomes only
RR 0.99 [0.72, 1.36]
4 studies · 7730 participants
Moderate

Serious adverse events: intussusception · children

RotaTeq showed no clear difference in serious adverse events: intussusception compared with placebo (low certainty).

3 findings from 1 review

Vaccines for preventing rotavirus diarrhoea: vaccines in use 2021 · Cochrane Headline outcomes only
RR 0.69 [0.35, 1.38]
9 studies · 73925 participants
Low
Vaccines for preventing rotavirus diarrhoea: vaccines in use 2021 · Cochrane Headline outcomes only
RR 5.01 [0.24, 104.29]
2 studies · 4082 participants
Very low
Vaccines for preventing rotavirus diarrhoea: vaccines in use 2021 · Cochrane Headline outcomes only
RR 0.33 [0.01, 8.16]
2 studies · 7488 participants
Low