Rifampicin plus pyrazinamide vs isoniazid
Treatment‐limiting adverse events · HIV‐negative people at risk of TB infection1
Rifampicin plus pyrazinamide leads to higher treatment‐limiting adverse events compared with isoniazid (high certainty).
1 finding from 1 review
- Rifamycins (rifampicin, rifabutin and rifapentine) compared to isoniazid for preventing tuberculosis in HIV‐negative… 2013 · Cochrane Headline outcomes onlyRR 3.61 [1.82, 7.19]2 studies · 368 participantsHigh