Findings

What do systematic reviews say?

6 questions · 11 findings · 1 reviews

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No studies found 0 · 0%GRADE not reported 8 · 72.7%Very low 0 · 0%Low 0 · 0%Moderate 3 · 27.3%High 0 · 0%

Resin infiltration vs Microabrasion

Masking effect / color improvement · Patients with white spot lesions or developmental enamel defects

Two studies compared resin infiltration with microabrasion, but no pooled or comparative effect estimate was reported (ungraded).

1 finding from 1 review

Efficacy of resin infiltration to mask post-orthodontic or non-post-orthodontic white spot lesions or fluorosis - a… 2021 All outcomes
no estimate extracted
2 studies
GRADE not reported

Resin infiltration vs In-office bleaching alone

Dentist satisfaction (masking effect) · Patients with dental fluorosis

Resin infiltration alone produced greater dentist-rated masking than in-office bleaching alone in one study (MD 3.97, 95% CI 3.33 to 4.61; ungraded).

1 finding from 1 review

Efficacy of resin infiltration to mask post-orthodontic or non-post-orthodontic white spot lesions or fluorosis - a… 2021 All outcomes
MD 3.97 [3.33, 4.61]
1 study
GRADE not reported

Bleaching before resin infiltration (bleaching + infiltration) vs Resin infiltration alone

Masking effect (esthetic improvement) · Patients with dental fluorosis

Bleaching before resin infiltration did not improve masking of fluorosis compared with infiltration alone (MD -0.30, 95% CI -0.98 to 0.39; moderate certainty).

1 finding from 1 review

Efficacy of resin infiltration to mask post-orthodontic or non-post-orthodontic white spot lesions or fluorosis - a… 2021 All outcomes
MD -0.30 [-0.98, 0.39]
2 studies
Moderate

Resin infiltration vs Untreated control (natural remineralization)

Optical/esthetic improvement (visual-tactile assessment) · Patients with post-orthodontic white spot lesions (WSL)

Resin infiltration produced significantly greater optical improvement of white spot lesions than untreated (naturally remineralizing) controls (SMD 1.24, 95% CI 0.59 to 1.88; moderate certainty).

4 findings from 1 review

Efficacy of resin infiltration to mask post-orthodontic or non-post-orthodontic white spot lesions or fluorosis - a… 2021 All outcomes
4 weeks to 6 months
SMD 1.24 [0.59, 1.88]
3 studies · 949 participants
Moderate
Efficacy of resin infiltration to mask post-orthodontic or non-post-orthodontic white spot lesions or fluorosis - a… 2021 All outcomes
4 weeks to 6 months · Visual analog scale (Senestraro et al. 2013)
SMD 2.34 [1.68, 3.01]
1 study · 66 participants
GRADE not reported
Efficacy of resin infiltration to mask post-orthodontic or non-post-orthodontic white spot lesions or fluorosis - a… 2021 All outcomes
4 weeks to 6 months · Spectroscopy delta-E (Knosel et al. 2013)
SMD 0.63 [0.26, 1.01]
1 study · 115 participants
GRADE not reported

Show 1 more finding

Efficacy of resin infiltration to mask post-orthodontic or non-post-orthodontic white spot lesions or fluorosis - a… 2021 All outcomes
4 weeks to 6 months · Modified enamel decalcification index (Cronan 2012)
SMD 0.98 [0.83, 1.13]
1 study · 768 participants
GRADE not reported

Resin infiltration vs Fluoride varnish

Optical/esthetic improvement (DIAGNOdent reading) · Patients (mainly children) with white spot lesions (WSL)

Resin infiltration produced significantly greater optical improvement than fluoride varnish (MD 4.76, 95% CI 0.74 to 8.78; moderate certainty).

3 findings from 1 review

Efficacy of resin infiltration to mask post-orthodontic or non-post-orthodontic white spot lesions or fluorosis - a… 2021 All outcomes
3 to 6 months
MD 4.76 [0.74, 8.78]
3 studies · 212 participants
Moderate
Efficacy of resin infiltration to mask post-orthodontic or non-post-orthodontic white spot lesions or fluorosis - a… 2021 All outcomes
3 to 6 months · Mild lesions, DIAGNOdent score <=14 (Ciftci et al. 2018; Giray et al. 2018)
MD 3.65 [0.82, 6.48]
2 studies · 172 participants
GRADE not reported
Efficacy of resin infiltration to mask post-orthodontic or non-post-orthodontic white spot lesions or fluorosis - a… 2021 All outcomes
3 to 6 months · Severe lesions, DIAGNOdent score >14 (Gozetici et al. 2019)
MD 13.15 [3.98, 22.32]
1 study · 40 participants
GRADE not reported

Bleaching before resin infiltration (bleaching + infiltration) vs Resin infiltration alone

Patient/dentist satisfaction · Patients with dental fluorosis

Patient/dentist satisfaction did not differ between bleaching-then-infiltration and infiltration alone (SMD -1.53, 95% CI -4.75 to 1.70; ungraded).

1 finding from 1 review

Efficacy of resin infiltration to mask post-orthodontic or non-post-orthodontic white spot lesions or fluorosis - a… 2021 All outcomes
SMD -1.53 [-4.75, 1.70]
2 studies
GRADE not reported