What do systematic reviews say?

Regular formoterol vs regular salmeterol

• Regular treatment with formoterol versus regular treatment with salmeterol for chronic asthma: serious adverse events 2012 · Cochrane Headline outcomes only
  no estimate extracted
  3 studies · 1116 participants
  Low

Regular formoterol vs regular salmeterol

• Regular treatment with formoterol versus regular treatment with salmeterol for chronic asthma: serious adverse events 2012 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 156 participants
  Very low

Regular formoterol and ICS vs same‐dose ICS

Regular formoterol and ICS showed no clear difference in all‐cause mortality compared with same‐dose ICS (moderate certainty).

• Inhaled steroids with and without regular formoterol for asthma: serious adverse events 2019 · Cochrane Headline outcomes only
  OR 1.25 [0.61, 2.56]
  32 studies · 35751 participants
  Moderate

Regular formoterol and ICS vs same‐dose ICS

• Inhaled steroids with and without regular formoterol for asthma: serious adverse events 2019 · Cochrane Headline outcomes only
  no estimate extracted
  10 studies · 4035 participants
  Low