Regular‐dose postoperative 5‐Fluorouracil vs control
Failure at 12 months ‐ combined surgery · participants with glaucoma surgery
1 finding from 1 review
- no estimate extracted2 studies · 118 participantsVery low
Findings
What do systematic reviews say?
22 questions · 24 findings · 1 reviews · Headline outcomes only
No studies found 4 · 16.7%GRADE not reported 0 · 0%Very low 2 · 8.3%Low 11 · 45.8%Moderate 7 · 29.2%High 0 · 0%
Regular‐dose postoperative 5‐Fluorouracil vs control
Intraocular pressure ( · participants with glaucoma surgery
3 findings from 1 review
- no estimate extracted2 studies · 118 participantsLow
- no estimate extracted2 studies · 112 participantsLow
- no estimate extracted1 study · 26 participantsModerate
Regular‐dose postoperative 5‐Fluorouracil vs control
Complications ‐ wound leak ‐ combined surgery · participants with glaucoma surgery
Regular‐dose postoperative 5‐Fluorouracil showed no clear difference in complications ‐ wound leak ‐ combined surgery compared with control (low certainty).
1 finding from 1 review
- RR 0.9 [0.36, 2.23]2 studies · 118 participantsLow
Regular‐dose postoperative 5‐Fluorouracil vs control
Complications ‐ hypotonous maculopathy ‐ combined surgery ‐ not reported · participants with glaucoma surgery
The review found no eligible studies for this question.
1 finding from 1 review
- no estimate extractedStudies not reportedNo studies found
Regular‐dose postoperative 5‐Fluorouracil vs control
Complications ‐ shallow anterior chamber ‐ combined surgery · participants with glaucoma surgery
1 finding from 1 review
- no estimate extracted2 studies · 118 participantsVery low
Regular‐dose postoperative 5‐Fluorouracil vs control
Complications ‐ epithelial toxicity ‐ combined surgery · participants with glaucoma surgery
Regular‐dose postoperative 5‐Fluorouracil may leads to higher complications ‐ epithelial toxicity ‐ combined surgery compared with control (low certainty).
1 finding from 1 review
- RR 3.04 [1.56, 5.92]2 studies · 118 participantsLow
Regular‐dose postoperative 5‐Fluorouracil vs control
Failure at 12 months · participants with glaucoma surgery
Regular‐dose postoperative 5‐Fluorouracil may leads to lower failure at 12 months compared with control (low certainty).
1 finding from 1 review
- RR 0.39 [0.26, 0.58]6 studies · 469 participantsLow
Regular‐dose postoperative 5‐Fluorouracil vs control
Complications ‐ hypotonous maculopathy ‐ high risk of failure ‐ not reported · participants with glaucoma surgery
The review found no eligible studies for this question.
1 finding from 1 review
- no estimate extractedStudies not reportedNo studies found
Regular‐dose postoperative 5‐Fluorouracil vs control
Complications ‐ shallow anterior chamber ‐ high risk of failure · participants with glaucoma surgery
Regular‐dose postoperative 5‐Fluorouracil showed no clear difference in complications ‐ shallow anterior chamber ‐ high risk of failure compared with control (moderate certainty).
1 finding from 1 review
- RR 2.41 [0.88, 6.58]2 studies · 239 participantsModerate
Regular‐dose postoperative 5‐Fluorouracil vs control
Complications ‐ epithelial toxicity ‐ high risk of failure · participants with glaucoma surgery
Regular‐dose postoperative 5‐Fluorouracil probably leads to higher complications ‐ epithelial toxicity ‐ high risk of failure compared with control (moderate certainty).
1 finding from 1 review
- RR 1.25 [1.12, 1.38]2 studies · 239 participantsModerate
Regular‐dose postoperative 5‐Fluorouracil vs control
Failure at 12 months ‐ primary trabeculectomy · participants with glaucoma surgery
Regular‐dose postoperative 5‐Fluorouracil probably leads to lower failure at 12 months ‐ primary trabeculectomy compared with control (moderate certainty).
1 finding from 1 review
- RR 0.21 [0.06, 0.68]2 studies · 112 participantsModerate
Regular‐dose postoperative 5‐Fluorouracil vs control
Mean intraocular pressure · participants with glaucoma surgery
The review found no eligible studies for this question.
1 finding from 1 review
- no estimate extractedStudies not reportedNo studies found
Regular‐dose postoperative 5‐Fluorouracil vs control
Complications ‐ wound leak ‐ primary trabeculectomy · participants with glaucoma surgery
Regular‐dose postoperative 5‐Fluorouracil showed no clear difference in complications ‐ wound leak ‐ primary trabeculectomy compared with control (low certainty).
1 finding from 1 review
- RR 0.47 [0.04, 4.91]2 studies · 112 participantsLow
Regular‐dose postoperative 5‐Fluorouracil vs control
Complications ‐ hypotonous maculopathy ‐ primary trabeculectomy · participants with glaucoma surgery
1 finding from 1 review
- no estimate extracted1 study · 62 participantsModerate
Regular‐dose postoperative 5‐Fluorouracil vs control
Complications ‐ shallow anterior chamber ‐ primary trabeculectomy · participants with glaucoma surgery
Regular‐dose postoperative 5‐Fluorouracil showed no clear difference in complications ‐ shallow anterior chamber ‐ primary trabeculectomy compared with control (low certainty).
1 finding from 1 review
- RR 0.47 [0.04, 4.91]2 studies · 112 participantsLow
Regular‐dose postoperative 5‐Fluorouracil vs control
Complications ‐ epithelial toxicity ‐ primary trabeculectomy · participants with glaucoma surgery
Regular‐dose postoperative 5‐Fluorouracil may leads to higher complications ‐ epithelial toxicity ‐ primary trabeculectomy compared with control (low certainty).
1 finding from 1 review
- RR 5.85 [2.04, 16.83]2 studies · 112 participantsLow
Regular‐dose postoperative 5‐Fluorouracil vs control
Complications ‐ wound leak · participants with glaucoma surgery
Regular‐dose postoperative 5‐Fluorouracil showed no clear difference in complications ‐ wound leak compared with control (low certainty).
1 finding from 1 review
- RR 1.38 [0.93, 2.04]6 studies · 469 participantsLow
Regular‐dose postoperative 5‐Fluorouracil vs control
Complications ‐ hypotonous maculopathy · participants with glaucoma surgery
The review found no eligible studies for this question.
1 finding from 1 review
- no estimate extractedStudies not reportedNo studies found
Regular‐dose postoperative 5‐Fluorouracil vs control
Complications ‐ shallow anterior chamber · participants with glaucoma surgery
Regular‐dose postoperative 5‐Fluorouracil showed no clear difference in complications ‐ shallow anterior chamber compared with control (low certainty).
1 finding from 1 review
- RR 1.84 [0.76, 4.46]6 studies · 469 participantsLow
Regular‐dose postoperative 5‐Fluorouracil vs control
Complications ‐ epithelial toxicity · participants with glaucoma surgery
Regular‐dose postoperative 5‐Fluorouracil may leads to higher complications ‐ epithelial toxicity compared with control (low certainty).
1 finding from 1 review
- RR 1.56 [1.36, 1.78]6 studies · 469 participantsLow