What do systematic reviews say?

Rapid susceptibility methods vs standard methods versus placebo

Rapid susceptibility methods showed no clear difference in mortality compared with standard methods versus placebo (low certainty).

• Rapid versus standard antimicrobial susceptibility testing to guide treatment of bloodstream infection 2021 · Cochrane Headline outcomes only
  RR 1.1 [0.82, 1.46]
  6 studies · 1638 participants
  Low

Rapid susceptibility methods vs standard methods versus placebo

Rapid susceptibility methods showed no clear difference in mortality (subgroup genotypic) compared with standard methods versus placebo (low certainty).

• Rapid versus standard antimicrobial susceptibility testing to guide treatment of bloodstream infection 2021 · Cochrane Headline outcomes only
  RR 1.02 [0.69, 1.49]
  4 studies · 1074 participants
  Low

Rapid susceptibility methods vs standard methods versus placebo

Rapid susceptibility methods showed no clear difference in mortality (subgroup phenotypic) compared with standard methods versus placebo (low certainty).

• Rapid versus standard antimicrobial susceptibility testing to guide treatment of bloodstream infection 2021 · Cochrane Headline outcomes only
  RR 1.37 [0.8, 2.35]
  2 studies · 564 participants
  Low

Rapid susceptibility methods vs standard methods versus placebo

Rapid susceptibility methods showed no clear difference in mortality (with stewardship) compared with standard methods versus placebo (low certainty).

• Rapid versus standard antimicrobial susceptibility testing to guide treatment of bloodstream infection 2021 · Cochrane Headline outcomes only
  RR 1.17 [0.81, 1.7]
  4 studies · 1404 participants
  Low

Rapid susceptibility methods vs standard methods versus placebo

Rapid susceptibility methods showed no clear difference in mortality (without stewardship) compared with standard methods versus placebo (low certainty).

• Rapid versus standard antimicrobial susceptibility testing to guide treatment of bloodstream infection 2021 · Cochrane Headline outcomes only
  RR 0.89 [0.35, 2.27]
  2 studies · 234 participants
  Low

Rapid susceptibility methods vs standard methods versus placebo

• Rapid versus standard antimicrobial susceptibility testing to guide treatment of bloodstream infection 2021 · Cochrane Headline outcomes only
  no estimate extracted
  4 studies · 1165 participants
  Low

Rapid susceptibility methods vs standard methods versus placebo

• Rapid versus standard antimicrobial susceptibility testing to guide treatment of bloodstream infection 2021 · Cochrane Headline outcomes only
  no estimate extracted
  5 studies · 1493 participants
  Low