Findings

What do systematic reviews say?

3 questions · 3 findings · 1 reviews

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No studies found 0 · 0%GRADE not reported 0 · 0%Very low 0 · 0%Low 1 · 33.3%Moderate 2 · 66.7%High 0 · 0%

RAS inhibitors vs thiazides

Stroke · patients with hypertension

RAS inhibitors probably leads to higher total stroke compared with thiazides (moderate certainty).

1 finding from 1 review

First‐line drugs inhibiting the renin angiotensin system versus other first‐line antihypertensive drug classes for… 2018 · Cochrane Headline outcomes only
RR 1.14 [1.02, 1.28]
1 study · 24309 participants
Moderate

RAS inhibitors vs beta‐blocker

Stroke · patients with hypertension

RAS inhibitors may leads to lower total stroke compared with beta‐blockers (low certainty).

1 finding from 1 review

First‐line drugs inhibiting the renin angiotensin system versus other first‐line antihypertensive drug classes for… 2018 · Cochrane Headline outcomes only
RR 0.75 [0.63, 0.88]
1 study · 9193 participants
Low

RAS inhibitors vs CCBs

Stroke · patients with hypertension

RAS inhibitors probably leads to higher total stroke compared with CCBs (moderate certainty).

1 finding from 1 review

First‐line drugs inhibiting the renin angiotensin system versus other first‐line antihypertensive drug classes for… 2018 · Cochrane Headline outcomes only
RR 1.19 [1.08, 1.32]
4 studies · 34673 participants
Moderate