What do systematic reviews say?

RAS inhibitors vs beta‐blocker

RAS inhibitors showed no clear difference in total heart failure compared with beta‐blockers (low certainty).

• First‐line drugs inhibiting the renin angiotensin system versus other first‐line antihypertensive drug classes for… 2018 · Cochrane Headline outcomes only
  RR 0.95 [0.76, 1.18]
  1 study · 9193 participants
  Low