Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

39 questions · 48 findings · 3 reviews

No studies found 1 · 2.1%GRADE not reported 0 · 0%Very low 3 · 6.3%Low 33 · 68.8%Moderate 10 · 20.8%High 1 · 2.1%

Psychotherapy as an adjunct to usual care vs usual care

Response (50% reduction in BDI) medium term (7 to 12 months)* · treatment‐resistant depression in adults

Psychotherapy as an adjunct to usual care may leads to higher response (50% reduction in BDI) medium term (7 to 12 months)* compared with usual care alone (low certainty).

1 finding from 1 review

Psychotherapy as an adjunct to usual care vs usual care

Response (50% reduction in BDI) long term (longer than 12 months)* · treatment‐resistant depression in adults

Psychotherapy as an adjunct to usual care may leads to higher response (50% reduction in BDI) long term (longer than 12 months)* compared with usual care alone (low certainty).

1 finding from 1 review

Psychotherapy as an adjunct to usual care vs usual care

Remission · treatment‐resistant depression in adults

Psychotherapy as an adjunct to usual care probably leads to higher remission (< 7 on HAMD or < 10 on BDI) medium term (7 to 12 months)* compared with usual care alone (moderate certainty).

2 findings from 1 review

Psychotherapy as an adjunct to usual care vs usual care

> 50% reduction in depressive symptoms · treatment‐resistant depression in adults

Psychotherapy as an adjunct to usual care may leads to higher response (50% reduction in depressive symptoms from baseline) short… compared with usual care alone (low certainty).

1 finding from 1 review

Dynamic‐Deconstructive Psychotherapy (DDP) vs treatment

Parasuicidalityno. of participants with parasuicide (last 3 months) · patients with borderline personality disorder

Dynamic‐Deconstructive Psychotherapy (DDP) showed no clear difference in parasuicidalityno. of participants with parasuicide (last 3 months) compared with treatment (low certainty).

1 finding from 1 review