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Evidence found and GRADE certainty

4 questions · 4 findings · 1 reviews · Gut

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Proton pump inhibitors (PPI) vs control

Number of participants with worsening scores in corporal atrophy · people with pre‐malignant lesions

Proton pump inhibitor showed no clear difference in number of participants with worsening scores in corporal atrophy compared with control (low certainty).

1 finding from 1 review

Proton pump inhibitors (PPI) vs control

Number of participants with worsening scores in corporal intestinal metaplasia · people with pre‐malignant lesions

Proton pump inhibitor showed no clear difference in number of participants with worsening scores in corporal intestinal… compared with control (low certainty).

1 finding from 1 review

Proton pump inhibitors (PPI) vs control

Increase in the number of participants with simple (diffuse) hyperplasia after treatment · people with pre‐malignant lesions

It is very uncertain whether proton pump inhibitor changes increase in the number of participants with simple (diffuse)… compared with control (very low certainty).

1 finding from 1 review

Proton pump inhibitors (PPI) vs control

Increase in the number of participants with linear/micronodular (focal) hyperplasia, comparing final biopsies with baseline biopsies · people with pre‐malignant lesions

Proton pump inhibitor may leads to higher increase in the number of participants with linear/micronodular… compared with control (low certainty).

1 finding from 1 review