Findings

What do systematic reviews say?

10 questions · 10 findings · 1 reviews · Airways

No studies found 0 · 0%GRADE not reported 0 · 0%Very low 0 · 0%Low 4 · 40%Moderate 6 · 60%High 0 · 0%

Improvement in WHO functional class · pulmonary arterial hypertension

Prostacyclin probably leads to higher improvement in WHO functional class compared with control (moderate certainty).

1 finding from 1 review

Prostacyclin for pulmonary arterial hypertension 2019 · Cochrane Headline outcomes only
OR 2.39 [1.72, 3.32]
8 studies · 1066 participants
Moderate

Headache+ · pulmonary arterial hypertension

1 finding from 1 review

Prostacyclin for pulmonary arterial hypertension 2019 · Cochrane Headline outcomes only
no estimate extracted
12 studies · 2351 participants
Moderate

Six‐minute walk distance · pulmonary arterial hypertension

1 finding from 1 review

Prostacyclin for pulmonary arterial hypertension 2019 · Cochrane Headline outcomes only
no estimate extracted
13 studies · 2283 participants
Low

All‐cause mortality · pulmonary arterial hypertension

Prostacyclin probably leads to lower mortality compared with control (moderate certainty).

1 finding from 1 review

Prostacyclin for pulmonary arterial hypertension 2019 · Cochrane Headline outcomes only
OR 0.6 [0.38, 0.94]
15 studies · 2554 participants
Moderate

mPAP (the higher the mPAP, the worse the pulmonary hypertension) · pulmonary arterial hypertension

1 finding from 1 review

Prostacyclin for pulmonary arterial hypertension 2019 · Cochrane Headline outcomes only
no estimate extracted
8 studies · 1132 participants
Low

PVR · pulmonary arterial hypertension

1 finding from 1 review

Prostacyclin for pulmonary arterial hypertension 2019 · Cochrane Headline outcomes only
no estimate extracted
7 studies · 658 participants
Moderate

Cardiac index · pulmonary arterial hypertension

1 finding from 1 review

Prostacyclin for pulmonary arterial hypertension 2019 · Cochrane Headline outcomes only
no estimate extracted
6 studies · 868 participants
Low

RAP · pulmonary arterial hypertension

1 finding from 1 review

Prostacyclin for pulmonary arterial hypertension 2019 · Cochrane Headline outcomes only
no estimate extracted
6 studies · 1060 participants
Moderate

Dyspnea · pulmonary arterial hypertension

1 finding from 1 review

Prostacyclin for pulmonary arterial hypertension 2019 · Cochrane Headline outcomes only
no estimate extracted
8 studies · 1521 participants
Low

Quality of life · pulmonary arterial hypertension

1 finding from 1 review

Prostacyclin for pulmonary arterial hypertension 2019 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 271 participants
Moderate