Findings

What do systematic reviews say?

7 questions · 7 findings · 1 reviews · Haematology

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No studies found 1 · 14.3%GRADE not reported 3 · 42.9%Very low 0 · 0%Low 2 · 28.6%Moderate 1 · 14.3%High 0 · 0%

Prophylactic platelet transfusions with low‐dose schedule vs high‐dose schedule

Number of participants with WHO grade 3 or 4 bleeding up to 30 days from study entry · People with a haematological disorder

Prophylactic platelet transfusions with low‐dose schedule showed no clear difference in number of participants with WHO grade 3 or 4 bleeding up to 30 days… compared with high‐dose schedule (low certainty).

1 finding from 1 review

Different doses of prophylactic platelet transfusion for preventing bleeding in people with haematological disorders… 2015 · Cochrane Headline outcomes only
RR 1.2 [0.82, 1.77]
1 study · 849 participants
Low

Prophylactic platelet transfusions with low‐dose schedule vs high‐dose schedule

Time to first bleeding episode (days) · People with a haematological disorder

1 finding from 1 review

Different doses of prophylactic platelet transfusion for preventing bleeding in people with haematological disorders… 2015 · Cochrane Headline outcomes only
no estimate extracted
1 study · 849 participants
GRADE not reported

Prophylactic platelet transfusions with low‐dose schedule vs high‐dose schedule

Mortality from all causes up to 30 days from study entry · People with a haematological disorder

Prophylactic platelet transfusions with low‐dose schedule showed no clear difference in mortality from all causes up to 30 days from study entry compared with high‐dose schedule (low certainty).

1 finding from 1 review

Different doses of prophylactic platelet transfusion for preventing bleeding in people with haematological disorders… 2015 · Cochrane Headline outcomes only
RR 1.33 [0.5, 3.54]
1 study · 849 participants
Low

Prophylactic platelet transfusions with low‐dose schedule vs high‐dose schedule

Number of platelet transfusions per participant up to 30 days from study entry · People with a haematological disorder

1 finding from 1 review

Different doses of prophylactic platelet transfusion for preventing bleeding in people with haematological disorders… 2015 · Cochrane Headline outcomes only
no estimate extracted
1 study · 849 participants
GRADE not reported

Prophylactic platelet transfusions with low‐dose schedule vs high‐dose schedule

Quality of life ‐ not reported · People with a haematological disorder

The review found no eligible studies for this question.

1 finding from 1 review

Different doses of prophylactic platelet transfusion for preventing bleeding in people with haematological disorders… 2015 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Prophylactic platelet transfusions with low‐dose schedule vs high‐dose schedule

Number of participants with at least 1 clinically significant bleeding event up to 30 days from study entry · People with a haematological disorder

Prophylactic platelet transfusions with low‐dose schedule showed no clear difference in number of participants with at least 1 clinically significant… compared with high‐dose schedule (moderate certainty).

1 finding from 1 review

Different doses of prophylactic platelet transfusion for preventing bleeding in people with haematological disorders… 2015 · Cochrane Headline outcomes only
RR 1.02 [0.93, 1.11]
1 study · 849 participants
Moderate

Prophylactic platelet transfusions with low‐dose schedule vs high‐dose schedule

Number of days on which bleeding occurred per participant up to 30 days from study entry · People with a haematological disorder

1 finding from 1 review

Different doses of prophylactic platelet transfusion for preventing bleeding in people with haematological disorders… 2015 · Cochrane Headline outcomes only
no estimate extracted
1 study · 849 participants
GRADE not reported