What do systematic reviews say?

Prophylactic vs selective blood transfusion

• Prophylactic versus selective blood transfusion for sickle cell disease in pregnancy 2016 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 72 participants
  Very low

Prophylactic vs selective blood transfusion

• Prophylactic versus selective blood transfusion for sickle cell disease in pregnancy 2016 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 72 participants
  Very low

Prophylactic vs selective blood transfusion

It is very uncertain whether prophylactic changes severe maternal morbidity (congestive cardiac failure) compared with selective blood transfusion (very low certainty).

• Prophylactic versus selective blood transfusion for sickle cell disease in pregnancy 2016 · Cochrane Headline outcomes only
  RR 1 [0.07, 15.38]
  1 study · 72 participants
  Very low

Prophylactic vs selective blood transfusion

It is very uncertain whether prophylactic changes perinatal death compared with selective blood transfusion (very low certainty).

• Prophylactic versus selective blood transfusion for sickle cell disease in pregnancy 2016 · Cochrane Headline outcomes only
  RR 2.85 [0.61, 13.22]
  1 study · 76 participants
  Very low

Prophylactic vs selective blood transfusion

Prophylactic may leads to lower sickle cell crisis (pain crisis) compared with selective blood transfusion (low certainty).

• Prophylactic versus selective blood transfusion for sickle cell disease in pregnancy 2016 · Cochrane Headline outcomes only
  RR 0.28 [0.12, 0.67]
  1 study · 72 participants
  Low

Prophylactic vs selective blood transfusion

Prophylactic showed no clear difference in sickle cell crises (acute splenic sequestration) compared with selective blood transfusion (low certainty).

• Prophylactic versus selective blood transfusion for sickle cell disease in pregnancy 2016 · Cochrane Headline outcomes only
  RR 0.33 [0.01, 7.92]
  1 study · 72 participants
  Low

Prophylactic vs selective blood transfusion

It is very uncertain whether prophylactic changes blood transfusion reaction compared with selective blood transfusion (very low certainty).

• Prophylactic versus selective blood transfusion for sickle cell disease in pregnancy 2016 · Cochrane Headline outcomes only
  RR 2 [0.54, 7.39]
  1 study · 72 participants
  Very low